Executives Summary of Warfarin and Vitamin K

                Vitamin K is also as the one the effective vitamin.  It plays significant role in the human body to providing the accurate amount of the protein.  Vitamin K is majorly used to clotting the blood in the human body to protecting from bleed in case of any injury. The excess use of the vitamin K makes the human blood thicker and sometime it can be the cause of any problem due to the thickness in the blood. This particular study is focusing on the interaction’s warfarin in vitamin K and it also discuss the several benefits of the vitamin K ion the human body. By the excessive use of the Vitamin K the INR can be decrease. If the person uses Vitamin K moderately the INR can be increase. The working principle of warfarin is discussed in effective manners in this essay.  The interaction of the vitamin K and Warfarin has been discussed extensively along with the table of the quantity of the vitamin K.  The role Warfarin and the proper recommendations are provided in this essay. The essay concluded as; all the vitamin K interacts with the body against the working principle of warfarin, but it is necessary for the blood clotting system. The body requires vitamin K to produce the essential blood clotting factors in an ineffective way.

Introduction of Warfarin and Vitamin K

        The vitamin can be used as the food because it helps to create more proteins by which body and bones can be strong. There are the several medicine which are commonly sued for stabling the quantity of the vitamin K in the human body. This particular study is focusing on the interaction’s warfarin in vitamin K and it also discuss the several benefits of the vitamin K ion the human body. But the excessive use of anything can spoil the human’s body. By the excessive use of the Vitamin K the INR can be decrease. If the person uses Vitamin K moderately the INR can be increase. This paper is also discussed about the various foods which have high amount of the vitamin K. This paper is also discussed about the working principle of warfarin.

        The working principle of warfarin and Vitamin K is against to each other in the body. In case of injecting warfarin input it is necessary to have the same amount of Vitamin K foods. In case of having any change in the diet, the Healthcare providers are required for consulted for adjustment of vitamin K and dose of warfarin in the blood (Ponchel, Burska, & Harrison, 2016).

        The measurement is required to wear blood clotting system and how much warfarin should be injected in the body. The quantity of Vitamin K and warfarin can be adjusted by having medications including nonprescription and prescription, controlling the diet, having herbal supplements, taking blood thinners (Drugs. com, 2019).

        The use of vitamin K helps to make proteins and keeps the body as well as bones strong.  It has a significant role in making the clot in case of bleeding. Vitamin K is pressure required for the good health and can be obtained from food containing vitamin K. Warfarin is known as coumadin that works as a thinner of blood and helps to prevent blood clotting from getting bigger (Heart. org, 2018).

The below given table is demonstrating the Very high in vitamin K as more than 800 mcg per serving

Source: https://uihc.org/health-topics/warfarin-your-diet-and-vitamin-k-foods

There few foods which are high in vitamin K as 400 to 800 mcg per serving

Source: https://uihc.org/health-topics/warfarin-your-diet-and-vitamin-k-foods

        The international normalized ratio (INR) determines the normal routine Blood Work in place of having warfarin. The health care service providers measure the amount of warfarin analyzing the blood clotting in the body. The regular use of warfarin pills can prevent the blood clotting from getting bigger. The common brand name of warfarin Coumadin (Ihtc. org, 2019).

        It is necessary to maintain the balance between amount of vitamin K and warfarin in the body. The imbalance between both could lead to health issues. Warfarin works against the working principle of Vitamin K and reduces the speed of blood clotting in the body (Pharmaceutical-journal. com, 2014).

        The present work deals with the interactions of warfarin and vitamin K in the human body and how it can be controlled with the appropriate use of food. The imbalance between both, as they behave opposite to each other, could cause serious health issues. The analysis is conducted to determine significant impact of interactions on the body and how it can be reduced.

Interactions of Warfarin and Vitamin K

        There is inverse relationship among the vitamin K and Warfarin because the Warfarin is use to thinning the blood meanwhile due to the excessive use of the vitamin K the blood can be thick in the veins.

        Commonly the Warfarin is used for preventing the harmful bold clots whenever these blood clots are created by the use of the vitamin K

        Vitamin K is essential for those reactions by which the Blood clots are formed and Warfarin (Coumadin) works by decreasing the activity of vitamin K

The common brand of the warfarin is known as the Coumadin which is used to ensuring the thinning the blood

The blood clot can be due to the vitamin K which helps to wounds don't bleed too much

Making the blood clot more slowly Warfarin works against vitamin K

        In order to analyses the working condition of warfarin it is necessary to conduct blood test to measure amount of warfarin in the blood and how much time it takes for the clotting of blood. The time taken by the blood for clotting is known as Prothrombin Time (PT) and International Normalized Ratio (INR) values (Clotcare. com, 2008).

        There are different sources of vitamin K and warfarin, for instance; black tea and green tea leaves contains vitamin K just before stepped into water. Consider the herbal and supplement products that contains vitamin K it is necessary to stop taking irregular amount of food before having consultancy with the doctor (Healthlinkbc. ca, 2019).

        The Prime range of products of INR is to identify the change in vitamin K and warfarin. The higher amount of vitamin K in the body loss INR value and takes less time to make the blood clot.  The low values of INR define that it requires some process to prevent the dangerous clotting of blood.  The increase in the INR values due to warfarin requires more time for the blood clotting (Mayoclinic. org, 2018).

        Due to high values of INR it can be concluded that warfarin is working well therefore the bleeding process is quick and easy. The rise in INR values could be dangerous for the health. In order to analyses the working principle and relationship between the vitamin K and warfarin it is necessary to determine the natural clotting process (Health. clevelandclinic. org, 2015).

        The use of vitamin K in the body have a significant role in the clotting process whereas on the other hand warfarin reduces the working efficiency of the blood clotting system and functionality of normal body. By reducing the ability of liver to use vitamin K in the functionality of blood the risk of forming blood clot can be reduced by warfarin (Webmd. com, 2014).

        A significant change in the body occurs with the intake of Vitamin K and it could be potentially dangerous.  By reducing the Normal amount of vitamin K in the human diet the INR value increases and it becomes difficult to manage warfarin therapy (Ponchel, Burska, & Harrison, 2016).

    The patients having low intake of Vitamin K suffers from strong fluctuation in their INR values. In order to maintain the consistent relation between the amount of vitamin K injection in the body and warfarin it is necessary to have consistent food diet system.  The process of anticoagulation clinician can be used for effective therapy and to measure effect of warfarin (Webmd. com, 2016).

        It is important to have consistent diet and adequate amount of intake level of vitamin K and warfarin. A normal adult man must have 120 micrograms of Vitamin K while on the other hand adult Women must have 90 micrograms of Vitamin K. In a normal human diet large amount of Vitamin C should be maintained by consuming drinks and food such as Kale Spinach, Brussels sprouts, Collards, Mustard greens, Chard, Broccoli, Asparagus, and Green tea (Ponchel, Burska, & Harrison, 2016).

        There are different drinks that can improve the effect of warfarin what leads to the bleeding problems. The small amount of drinks including cranberry juice and alcohol should be avoided. The doctor should be consulted in case of any changes in the diet for the counter medication, supplements particularly herbal supplements and vitamins. Warfarin have significant impact on the body, and it should be managed and maintained with the amount of vitamin K in the blood (Ponchel, Burska, & Harrison, 2016).

Role of warfarin and how drink warfarin in patients of Warfarin and Vitamin K

            Warfarin should be used in the prescribed amount of the medication and should prevent harmful blood clotting in the blood. The beneficial blood clot should be prevented and stop the bleeding in the deep vein and embolism. The warfarin interface between formation of blood clot and it is called anticoagulant (Ponchel, Burska, & Harrison, 2016). A number of peoples preface to anticoagulant as blood thinners. The formation of clots in the blood is a complex process that involves different substances clotting factors.  Warfarin decreases the normal ability of blood clot by blocking the formation of vitamin k. Vitamin k is an essentially required for the clotting factor and to prevent the bleeding (Ponchel, Burska, & Harrison, 2016). The medication should be used to block the clotting factor particularly harmful clothes in that can become greater in size.  The goal of warfarin therapy is to decrease the clotting tendency in the blood and to prevent the formation of clots in the blood. The blood test can be used to determine the prothrombin time test, or protime (pt) that can be referred as INR value for the standardized size (Health. clevelandclinic. org, 2015). There must be standardized and measured amount of warfarin in the blood on regular basis. The dose of warfarin should be maintained on the regular basis and it should not be increased or decreased unless it is inspected by the healthcare provider. There are some major complications with using the warfarin INR clotting and it is particularly due to the extensive anticoagulation process (Ponchel, Burska, & Harrison, 2016). The excessive bleeding can occur in any area of the body in case of irregular amount of warfarin in the blood. There are different types of medications and each type of medication can alter the effectiveness of INR values and warfarin (Ponchel, Burska, & Harrison, 2016).

        Warfarin interacts with different modes of diet specially food and alcohol in different ways. Alcohol intake can affect the metabolism system of blood. The use of alcohol in body increases antiplatelet effect that increases the risk of major bleeding and INR value increases and it is at the top maximum values (Health. clevelandclinic. org, 2015). There are some types of food that can interface with the effectiveness of warfarin and one of the important factors is to eat according to the requirement according to the diet provided by healthcare provider (Ponchel, Burska, & Harrison, 2016). The most the important factor in the analysis is that healthcare provider should be remaining in contact in case of any imbalance between the amount of vitamin k and warfarin. The potential increase in the risk of blood clot increases due to the less effectiveness of warfarin. The highest amount of vitamin k in the associated with the leafy vegetables and green vegetables. It is not necessary to avoid all the food and all green fruit, but the most important point is to maintain the amount of vitamin k and warfarin in the daily diet (Mayoclinic. org, 2018).

        Despite being very effective warfarin treatment imposes some issues particularly related to the formation of blood clots.  The response relationship of warfarin is unpredictable, and the activity can be monitored in an effective way (Ponchel, Burska, & Harrison, 2016). Warfarin directly relates to the drug metabolizing system, polymorphism in cyp2c9 gene results in the higher warfarin hypersensitivity, activity of drug metabolizing enzyme, polymorphisms in vkorc1 due to intake of warfarin can results in the different levels of expression of the protein. In some cases, warfarin accumulates in the liver and results in the oxidative metabolism and reduces the efficiency of the body and blood system of the body (Ponchel, Burska, & Harrison, 2016). The higher maintenance of blood is required due to anticoagulant effect of warfarin in the blood. There are different factors having impact on the anticoagulant effect of warfarin’s and these factors includes the states of diseases and it gets affected by the intake of vitamin k and warfarin (Clotcare. com, 2008). The fluctuation in the dietary conditions and intake of warfarin can result in the alteration of absorption levels, clearances, and metabolism system of body. The variability in the response provided by the different levels of intake can be due to anticoagulant response and requires monitoring of all the therapeutic responses (Clotcare. com, 2008).

        The diet and nutrition of a normal human can affect the treatment of warfarin. It is important to keep the way supplements and vitamins and food intake steady through the treatment. Level of vitamin k can promote the treatment and can reduce the effectiveness of warfarin (Ponchel, Burska, & Harrison, 2016).  The effective way is to maintain the amount of vitamin k and warfarin instead of avoiding any food and products. In the food there are different levels of vitamin k data from moderate to higher levels however there are some food that have no effect on the flowers of vitamin k and warfarin (Mayoclinic. org, 2018). The patients who are experiencing bleeding complications faces increase in INR values and higher contamination of food beyond the limit of consumption. There are different levels for receiving the warfarin in the preferable limit of food. The food and medication can increase the interaction of warfarin with the blood at different levels (Ponchel, Burska, & Harrison, 2016).  Minimize potential of interaction can reduce the protein effectiveness in the body and requires complete assessment from the doctor regarding therapeutic duplication maximization an exceeded level of recommended therapeutic duplication maximization. There are different levels of interaction between herbal supplements, medicines, food, and warfarin (Webmd. com, 2016). The effectiveness can be organized on the basis of interaction between the herbal supplements and warfarin. The considerable factor is the eating patterns and regular intake of warfarin. The Healthcare provider monitor is a condition and provide adjustment for the warfarin conditions in the blood.  The number of risk factors associated with the blood clot can be increased by the several considerations (Ponchel, Burska, & Harrison, 2016).

Recommendation of Warfarin and Vitamin K

        The heart patient should be very conscious for taking the blood thinners particularly warfarin. The blood thinners are often prescribed by the doctors to reduce the development of harmful blood clotting system. The sudden increase in intake of vitamin k in the diet consequently reduces the effect of warfarin. The vitamin k is essential part of diet and chemical processes reduces the forming of blood clots in the blood (Ponchel, Burska, & Harrison, 2016; Health. clevelandclinic. org, 2015). The leafy green vegetables, consistent exercise and work, balance and diet, consultancy with the doctor, can reduce the negative effect of imbalance between vitamin k and warfarin in the blood. Tips to manage the vitamin k intake are mentioned below,

        The user should pay attention to the labels of food before taking. The food having vitamin k should be included in the regular diet. For instance, the regular intake of vitamin k should be maintained by food. It is necessary to discuss the regular sources of vitamin k as well as an irregular sources of vitamin k in your diet with the doctor so the dosage of warfarin can be adjusted based on higher and low vitamin k in the body. Different vegetables contain multivitamins and it should be used to maintain the level of vitamins in the body (Health. clevelandclinic. org, 2015).

        The user should be aware of herbal supplements specially omega-3 supplements (epa/dha). The supplement should be discussed with the doctor either they have interference with the blood thinners or not for instance aspirin works as blood thinner (Ponchel, Burska, & Harrison, 2016).

        The blood thinner should be taken in the consistent way in case of higher intake of vitamin k. The regular use of vitamin k should be maintained along with the dosage of warfarin (Health. clevelandclinic. org, 2015).

        The US Department of agriculture provides extensive information about the amount of vitamin k present in the food particularly in the vegetables and leafy greens. The better understanding of blood thinners and food having higher as well as moderate level of vitamin k can provide better understanding for the level of maintenance and equilibrium in the blood (Ponchel, Burska, & Harrison, 2016). Some vegetables along with the amount of vitamin are mentioned below,

 

Conclusion of Warfarin and Vitamin K

            All the vitamin K interacts with the body against the working principle of warfarin, but it is necessary for the blood clotting system. The body requires vitamin K to produce the essential blood clotting factors in an ineffective way.  Therefore, people having bleeding tendency Tesla amount of Vitamin K. Warfarin along with Vitamin K interacts with each other in a long time and results in the formation of Clots. The intended effect of the therapy is to increase intake of Vitamin K and warfarin at the same time works against the action of medication. The interaction between warfarin and vitamin K is opposite to each other and can reduce the working efficiency of body. The proper maintenance of diet is essentially required to reduce the interaction between warfarin and vitamin K.