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It has been observed in this study that the
properties of the properties of the incorporated materials can be used for
improving the mechanism of the drugs binding. Such as the binding sites for
polar drugs can be creates by the incorporation of the ionic monomers for
binding too as depicted in the below figures. This figure is shows the drugs
can be retain by the lens until it will placed onto eye. For examples the MAA is known as the co
monomers which is usually used for the formation of the hydrogels. It also has
an ionic group for facilitating the binding of the drugs. The new materials is also used for the copolymerized cyclodextrins to
introduce the both characters as; hydrophobic and hydrophilic for the contact
lenses.
Source:
Figure 8: Mechanism of Drug-binding and releasing for
a contact lens
The above shown figure is representing the
mechanism of the releasing and biding of the drugs in the contact lenses by
suing the ionic sites within the structure.
The research study also observed the
Technologies for the Emerging CL Materials which are usually two types of the
methods as post and pre addition methods. The interpenetrating hydrogels are
cartel by the two types of the gels by inter connecting the networks of the
gels together. It can be resulted as the composites of the ne gel as shown in
the below figure. Basically the network
of the one gel is tangled along with other, as compare to the traditional copolymer gel and its formation. It
is understood but5 create significant difference as two polymers are required
for the formation of the double network gel along with the various functional
groups. It cannot copolymerized.
This figure is showing that all of these
hydrogel can be after formed by using the post and pre formation of the one
gel.
Source:
Figure 9:
double-network hydrogel combines the properties of two hydrogels
The below given pie charts is expressing the
percentages of the mostly usable materials for the contact lenses in the different
attractive colors. As the orange colors which have occupied the most of the
surface of the figure is representing the percentages of the Silicone
hydrogel lenses, it also shows that the 64% of the total materials is using for
the Silicone hydrogel lenses. The blue color is represents the percentages of
the PMAA lenses which is 22% and grey color represents the percentages of the
materials of the GP lenses and yellow color represents the Hybrid contact
lenses which is 2 % only.
Conclusions of contact lenses
It is concluded that the people who wears contact lenses are also able to wear other eye wear devices such as sunglasses or goggles, depend on their option deprived of having to match them with any lenses from the doctor’s prescription or concern around the affinity with glasses. If compared with glasses, contact lenses claimed to be more comfortable for the people to wear in the course of sports and vacation activities outdoor by offering a varied field of interpretation, a smaller amount possibility of eviction, a lesser amount of sensitivity to fogging, sliding off from the face because of sweating, and also dirt. The materials which is used to making the contact lenses also concluded in this study. Silicone hydrogel lenses are most useable lenses material which is commonly using in the entire world particularly in the United States.
It is concluded that the modern CL (Contact
Lenses) investigation purposes to deliver better treatments in ophthalmic or
advance the current matters around contact lenses. Generally, modern CL
resources are defined as an advancement of the famous materials of lens which
based on HEMA along with the silicone hydrogels. These types of hydrogels
imbedded numerous bioavailable elements, like “PEG, HA, chitosan,
β-cyclodextrin, cellulose, and other moieties” which are quite
biocompatible because of their characteristic chemistry.
The biomaterials area is considered to be
stimulating and active, where innovative and enhanced biocompatible,
drug-shipping materials are continually get settled. One point that might be
the largest obstacles to overwhelmed is from the price and realism of
integrating a class to an innovative lens. Certain highlighted developing
fields associated to CLs because the materials elaborate or might just have
been installed to CLs. The implementation of new developed procedures could
deliver for further solutions to precise issues for CLs: fresh growth
materials, exterior contouring, etc.
The CL materials are currently strong and adaptable, and are therefore
fit for the enlightening the built-up procedures. In conclusion, upcoming CL
materials expected to endure to drive the limitations of the biocompatibility
along with the skills of materials to better modify to the requirements of an
increasing people which are using CL.
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