Pathophysiology/etiology of Urinary Tract
Unitary tract infection is referred to as asymptomatic bacterial
infection in the urinary tract. The issue includes lower urinary tract
infection that is known as cystitis and the upper Unitary tract infection that
is known as acute pyelonephritis. The cystitis is symptomatic bladder infection
and acute pyelonephritis is the kidney infection. The classification of Unitary
tract infection is based on the symptoms and the area suggested by the
terminology. Asymptomatic bacteriuria is identified mainly in patients having
two consecutive urine cultures showing > 100,000 CFU/, L urine but it is not
simple as compared to UTI. It is treated in a single way that is before the
urological operation, immunocompromised patients and women. Unitary tract
infection may become complicated if the symptoms emerge with pyelonephritis.
Expect the distal urethra, the tract becomes normally sterile because of the
host defenses against bacterial colonization (Lima & Manzoni,
2014).
Etiology of Urinary Tract
Etiology is an issue that occurs (80-90%) due to infection of Escherichia
coli species. The other usual causes include Proteus mirabilis, Klebsiella,
Staphylococcus saprophyticus and Enterococcus. Periurethral colonization is
carried out by the pathogen that appears on the initial steps of the cascade
that event leads to UTI. In the causative organisms, the natural GI tract
process is considered that act as the natural reservoir for the UTI. Risk
factors include iatrogenic, behavioral, genetic and anatomic issues (Mulvey, Klumpp,
& Stapleton, 2017).
Pathophysiology of Urinary Tract
Pathogenesis of the urinary tract infection includes several considerations
including acute kidney injury, pyelonephritis, ascension, uroepithelium
penetration, and colonization. Acute kidney injury is due to inflammatory
cascade, tubular obstruction, and interstitial edema. The pyelonephritis is the
infection of renal parenchyma that cause pyelonephritis. Ascension is the
bacterial colonization that occurs due to bacteria in the kidney. Uroepithelium
penetration is due to fimbria that allows bladder for penetration and
replication (Pathophys. org, 2019).
Prevalence / Statistics of the Disease Worldwide/ within the
GCC or Saudi Arabia, or in JHAH of Urinary Tract
According to the statistical analysis, the appropriateness and urinary
tract infection treatment are measured in the emergency department of Saudi
Arabia. In Saudi Arabia, urinary tract infection (UTI) is becoming a serious
health issue and it induces an impact on the millions of people every year. The
overall prevalence of urinary tract infection is 9.9%. The analysis showed
1,449 diagnosed patients with UTI including pediatric (18.6%), elderly (22.2%)
and adult (59.2%). In this situation, three main types of antibiotics were
prescribed including fluoroquinolone (22%), penicillin (26%), and cephalosporin
(39%) (Alanazi, 2018). There are two types of Unitary tract defense mechanisms including urine
and mucosal immunity.
Urinary tract host defenses
|
Urine
|
Mucosal
immunity
|
Acidic pH that
is intolerable by the pathogens
|
Urothelial
secretion of chemokines and cytokines
|
The high
osmolality of urine
|
Mucopolysaccharide
lining for the increase of penetration of bacteria.
|
Attachment of
competitive inhibitors with the uroepithelial cells
|
Mucosal
IgA
|
Mechanical
flushing of urine flow
|
In the case of
males, prostatic secretions that contain the bactericidal zinc and the
urethra
|
Signs and symptoms (300)
There is a number of
symptoms of urinary tract infections that don’t always cause issues urinary
system (Mayoclinic. org, 2019). The major symptoms are
listed below,
1.
Burning sensation during urinating
2.
The persistent urge in urinating
3.
Smalls and frequent amounts of urine
4.
Cloudy urine
5.
Muscle aches
6.
Abdominal pains
7.
Urine that appears the cola-colored, bright pink and red color sign
8.
Pelvic pain particularly in women
9.
Strong smelling urine
Part of urinary tracts
that are affected
|
Symptoms and signs
|
Bladder (cystitis)
|
a)
Lower abdomen discomfort
b)
Blood in urine
c)
Pelvic pressure
d)
Painful and frequent urination
|
Kidney (acute
pyelonephritis)
|
a)
Vomiting
b)
High fever
c)
Upperside and back pain
d)
Shaking and chills
e)
Nausea
|
Urethra
|
a)
Discharge
b)
Burning with the urination
|
Prevention of
Urinary Tract
There are several steps to
reduce the risk of urinary tract infections.
1. Drink plenty of water and liquid
Drinking more water can
help in reducing and diluting the urine and then ensure you are urinating
frequently. This process will remove bacteria from the body (Lima & Manzoni, 2014).
2. Empty bladder of Urinary Tract
Keep the bladder empty that
will remove bacteria from the body.
3. Drink cranberry juice of Urinary Tract
Some studies and
researches concluded that cranberry juice prevents urinary tract infection UTI.
Diagnostic procedures/tests of
Urinary Tract
Different testing and diagnostic method can be used
to reduce the problem and the main focus of these methods and procedures is to
diagnose urinary tract infection.
1. Blood sample analysis
The doctor and expert can ask for the urine samples
to be analyzed in the labs. The analysis considers the number of white blood
cells, bacteria, and red blood cells. The analysis can be used to prevent the
potential combination of samples with the other samples. In the process, the
doctors ask to wipe the genital area by using an antiseptic pad to collect to
the midstream urine (Mulvey, Klumpp, & Stapleton, 2017).
2. Growth of bacteria
In this lab analysis, urine is used to be considered
in the urine culture. The test analysis reveals the type of bacteria that can
cause infection and medication in a proper way is the most effective method to
overcome the issue.
3. CT scan and MRI
To identify the issue and solution of the issue it
is important to find the location. The computer can be used to design the
outcomes of the test. The doctor can analyze reasons for abnormality in the
urinary tract by using ultrasound, computerized tomography scan and magnetic
resonance imaging (MRI). The doctor can
use a contrast dye to highlight the structure of the urinary tract (Healthline.
com, 2017).
4. Ultrasound
A device of ultrasound that is called transducer is
passed over the abdomen and it generates ultrasound waves to generate the image
of urinary tract organs and it is displayed on the monitor.
5. Intravenous pyelogram
(IVP)
This treatment involves injecting dye into the body
and the dye pass through the urinary tract and X-ray analysis of the abdomen is
carried out to highlight the urinary tract.
6. Cystoscope
In the case of recurrent UTIs, the doctor recommends
performing the cystoscopy. The process uses a thin tube lens to see inside the
urethra and bladder. The cystoscope is inserted in the urethra and then passes
through the bladder to check the level of the issue in the body.
Medical treatment/management (200)
1) Simple
infection of Urinary Tract
The first treatment method
deals with antibiotics to overcome urinary tract infections. The drugs
prescribed in the treatment depend on age, health condition, and illness type.
The drugs recommended in the simple type of urinary tract infection include
Fosfomycin (Monurol), Ceftriaxone, Trimethoprim/sulfamethoxazole (Bactrim,
Septra, others), Nitrofurantoin (Macrodantin, Macrobid), and Cephalexin
(Keflex). Another group of antibiotics is called fluoroquinolones that include
levofloxacin (Levaquin) and ciprofloxacin (Cipro). These methods have
outweighed benefits (Mulvey, Klumpp, & Stapleton, 2017).
2) Frequent
infection of Urinary Tract
If a patient undergoes frequent Urinary tract
infection (UTI) then doctors recommend some other solutions. The use of low
dose antibiotics is the first treatment step that remains to continue for the
six months and sometimes more than six months. The treatment and self-diagnosis
is another strategy to remain in touch with the doctors. Vaginal estrogen
therapy is used in the case of post-menopausal (Lima & Manzoni, 2014).
3) Severe
infection of Urinary Tract
In the case of the severe
stage of Urinary tract infection (UTI) the doctors recommend continuous
treatment in hospital with intravenous antibiotics used in the hospitals.
When comparing to the
international best practice guidelines provided to the doctors the best
strategy is to measure the issue and then have complete treatment (Naber
& Johansen, 2018). The doctors measure the level of seriousness and which organism is
causing the infection from the results of the initial test and then use the
reports. In most of the causes, the main issue is bacteria that can be treated
by using antibiotics. In some other cases, viruses and fungi can also cause
Urinary tract infection (UTI). The viral type of Urinary tract infection (UTI)
is treated by proper medication that is called antivirals. Most often, the
antiviral cidofovir is the only choice to treat viral UTIs. The antifungals are
used to treat the Urinary tract infection (UTI) that is caused by fungi (Pathophys. org, 2019).
Compare to International Best Practice Guidelines, e.g. NICE
/ CDC guidelines
Patient Presentation
Patient information
Description of disease/condition
Comparison to a textbook case
Contrast to a textbook case
Expected prognosis
Nursing Assessment:
Safe environment
|
Communication
|
Breathing
|
Eating & drinking
|
Elimination
|
Washing & dressing
|
Thermoregulation
|
Mobilization
|
Work & play/social
|
Expressing sexuality
|
Sleeping
|
Dying / Pain
|
Normal findings
|
Abnormal findings
|
|
|
|
|
|
|
Related to ADL’s (activities of daily living)
….this can be done separately or
included in your ADL boxes
Relate findings to the disease process
….this can be done separately or
included in your ADL boxes
Nursing Care Plan
Three nursing diagnosis
This can be done either with 1
diagnosis, goal or evaluation per page or as a table (see below)
A. Prioritize nursing diagnosis
B. Nursing Care Plan
i.
Diagnosis
ii.
Goal/s
iii.
Interventions
Evaluation/Outcomes
Diagnosis
|
Goal
|
Implementations
|
Evaluation
|
1
|
|
|
|
2
|
|
|
|
3
|
|
|
|
Conclusion of Urinary Tract:
Summarize of current condition
Summing up all
the discussion from above, it is concluded that urinary track injection is
extremely important for the patients
that are struggling with a particular disease.
In this paper, there is complete information about the symptoms of this disease.
The classification of Unitary tract infection is based on the symptoms and the
area suggested by the terminology.
Unitary tract infection may become complicated if the
symptoms emerge with pyelonephritis. Expect the distal urethra, the tract
becomes normally sterile because of the host defenses against the bacterial
colonization
Etiology is an issue that occurs (80-90%) due to infection of
Escherichia coli species. The other usual causes include Proteus mirabilis,
Klebsiella, Staphylococcus saprophytic us and Enterococcus. Periurethral
colonization is carried out by the pathogen that appears on the initial steps
of the cascade that event leads to UTI. In the causative organisms, the natural
GI tract process is considered that act as the natural reservoir for the UTI.
The pyelonephritis is the infection of renal parenchyma that
cause pyelonephritis. Ascension is the bacterial colonization that occurs due
to bacteria in the kidney.
In Saudi Arabia,
urinary tract infection (UTI) is becoming a serious health issue and it induces
an impact on the millions of people every year. The overall prevalence of
urinary tract infection is 9.9%. Then after this, there is comprehensive information
about the diagnosis procedure in detail.
Patient & family teaching of Urinary Tract:
This is what you teach the patient;
include any patient handout or PTR’s you used during the patient's stay. As it
has been discussed in the above section that how dangerous this disease is for
the patients for that case, the family of the patients has to take a proper
look on the recommendations for the patients. This is an extremely harmful
disease and the patient has to be extremely careful while dealing with such
disease.
The parents of the patients and other
family members have to follow all kinds of instructions related to the disease.
The doctor will provide proper information about the medicine schedule and the
members of the family have to provide proper information about the condition of
the patient.
Patient & family response to teachings:
The response of the family must be
positive according to the teachings of the doctor. The family member must have
to stay positive and deal with the condition in an efficient way. Moreover, if
there is a need for any kind of injection so they must have to provide him
according to the recommendation of the patient. If the family member will stay
completely positive then it will be extremely easy for them to overcome such
disease in less time.
Furthermore, the family has to give
proper information about the regular condition and situation of the patient.
This is because through analyzing these conditions he will give them proper
recommendations about what they have to do for the future. The next thing is that
the family members also have to follow all recommendations inefficient way for
the welfare of the patient.
How you assessed their
understanding?
This is one of the most difficult tasks to
assess their understanding. But it can be done easily by just following the
recommendation and details given by the doctor. If you have any kind of
misunderstanding just consult the doctor immediately without any hesitation.
The main reason is that it is an extremely sworn condition and the family
member are not able to take any kind of risk regarding the main problem. This
is the reason why it is extremely important to gain proper knowledge about the
condition of the patient.
Expectations after discharge of Urinary Tract:
Discharge home and
follow up appointment- this is only the basics.
You must include
information regarding returning to work/school, driving a car, having more
pregnancies, lifting, bending, further education or counseling required, etc.
It can be noted that
the family members must have to keep positive expectations after the discharge.
Then after this, the doctor will give a proper recommendation about future
appointments. The family members of the patients must have to stay positive and
check your patients regularly according to the recommendation of the
doctor.
The classification of Unitary tract infection is based on the
symptoms and the area suggested by the terminology. Asymptomatic bacteriuria is
identified mainly in patients having two consecutive urine cultures showing
> 100,000 CFU/, L urine but it is not simple as compared to UTI. This
disease is extremely critical. In that case, the doctor has to give him special
medicine in case of any problem to the patients.
After discharging the patient, the doctor will give a proper
recommendation about the treatment and regular checkup of the patient. Through
this, it will become extremely easy to check the main problem in the health of
the patient. The doctor will provide
proper information about the medicine schedule and the members of the family have
to provide proper information about the condition of the patient. Then after
this, it is the main duty of the doctor to check the patient and also give him
proper medication according to the demand.
References of Urinary Tract:
Alanazi, M. (2018). An evaluation of
community-acquired urinary tract infection and appropriateness of treatment in
an emergency department in Saudi Arabia. Therapeutics
and Clinical Risk Management, 14(01), 01-10.
Healthline. com. (2017). Everything You Need to Know About Urinary
Tract Infection. Retrieved from www.healthline.com:
https://www.healthline.com/health/urinary-tract-infection-adults#risks-for-women
Lima, M., & Manzoni, G. (2014). Pediatric Urology: Contemporary Strategies
from Fetal Life to Adolescence. Springer.
Mayoclinic. org. (2019). Urinary tract infection (UTI).
Retrieved from www.mayoclinic.org:
https://www.mayoclinic.org/diseases-conditions/urinary-tract-infection/symptoms-causes/syc-20353447
Mulvey, M. A., Klumpp, D. J., &
Stapleton, A. E. (2017). Urinary Tract
Infections: Molecular Pathogenesis and Clinical Management. Wiley.
Naber, K. G., & Johansen, T. E.
(2018). Antibiotics and Urinary Tract
Infections. Multidisciplinary Digital Publishing Institute.
Pathophys. org. (2019). URINARY TRACT INFECTION (UTI) » PATHOGENESIS
OF URINARY TRACT INFECTION. Retrieved from www.pathophys.org:
http://www.pathophys.org/uti/uti-patho/