RESULT
Number
of different articles were being reviewed here in this study, first of all I
looked for the basic diabetes type 2 articles and their prevalence in the whole
world that how this disease takes place and how much of the people it is affecting
yearly. All the data has been reviewed successfully in the literature review
part. Later on, I looked particularly for the Diabetes type 2 in china and I
found many articles on which different studies were being made. But here I want
to add one more thing that I only wanted those articles which were latest and
showed the reasons that why the diabetes type 2 is increasing so rapidly in
china on such a large scale. What are the main reasons to make this happen?
Well, I excluded articles from the list those didn’t show the latest research
and after that I also started excluding the articles that were showing
different studies apart from china. There were many articles that were not accessible
easily and they were charging some amount to study them they were not free so I
also excluded those articles from my study. Furthermore, many of the dull-text
articles were also been excludes with number of several reasons like they were
not specifically about Diabetes type 2, they about other type of diabetes.
Other than this, genetics, ethnicity, and medical treatments were the other
reasons due to which the articles got excluded. Last reason due to which some
other articles also got excluded was that I was not taking the studies about
the old people who were above 60 years and the small children who were below
the age of 16 to 17 years. So in total, I extracted my studies or data from
almost 30-35 different articles.
There
are number of different elements in the environment that have been posited
towards the influence of type 2 diabetes mellitus also called as T2DM. This
whole systematic review helps in summarizing the evidence on the determinants
of environment of T2DM that have been identified in four different kind of the
databases. It also helps in proposing out a theoretical framework that
illustrates the link between T2DM and environment, it also briefly discusses
about some of the methodological challenges along with their potential solutions
and opportunities for the future research. Air pollution, physical activity
environment, food along with the different roadways proximity were considered
to be the most common environmental factors that have been studied. Burden of
this diabetes 2 is increasing very highly worldwide and specially in China by
posing the socioeconomic along with the health challenges as well. Number of
the people with this disease is estimated to be increased from 415 million in
2015 year towards the 642 million by the year of 2040. This type 2 diabetes
mellitus T2DM is being characterized by the excess level of sugar in the blood
accounts for around 90 percent of the cases. T2DM can even cause a much severe
damage to the whole body parts like eyes, kidneys, heart along with the
vascular system as well. It shows up that the Diabetes is increasing
drastically according to the different studies in china and it needs to be
controlled as soon as possible. (Jia, 2019)
Increasing
prevalence of Diabetes 2 has now become one of the most global public health
concern in the 21st century, another study has been conducted and it shows
china that is the most populous country has been ranked on number one with an
estimation of about 109.6 million adults having this diabetes 2. From the last
three decades, rate of diabetes has increased sharply in china as compared to
the other countries. Prevalence of this diabetes in china was reported way less
than 1% in ratio back in 1980, then in 2001 the ratio almost 5.5%, in 2008 the
percentage increased and it was 10.9%. But now according to the 2013 survey it
has been shown, 4% of the adults have already been diagnosed with the diabetes,
almost 6.9% of the patients have come to know about this disease recently. (Ma, 2014)
As
we all know that china is multiethnic country and the survey was compared with
other different races and it was found out that crude prevalence of diabetes
was almost 14.7% in the majority of the group like Chinese Han which was much
higher than in most of the minority ethnic groups that includes Zhuang, Tibetan
and Muslims. Crude occurrence of this prediabetes disease was again higher in
the Chinese Han ethnic group as well. Tibetan participants were the ones that
had a very much low prevalence of the diabetes as well as the prediabetes that
is 4.3% and 31.3%. Another thing that is to be noted down here is that
prevalence of diabetes 2 in the Manchu group was almost the same as that in the
Chinese Han group, and the ratio of prediabetes was way more or can be called
as much higher. (Mohan, 2009)
Results
from one another shows that prevalence of the diabetes 2 in china’s young
people is considerably high and still chances are much of them to get
increased. Prevalence of the diabetes 2 in the age group of 20-39 was almost
3.2%, according to another survey that was being done shows that ratio was
increased to 5.9% with the passing years. Prevalence of prediabetes also
increased from the ratio of 9% to 30% almost as the years are passing.
Young
people who suffer from this disease of diabetes 2 are at much higher risk of
the chronic complication and this is another major cause of the morality as
well as the indisposition in disease. According to another study that has been
conducted shows that patients who have young onset of the diabetes had much
higher mean concentration of the HbA and the cholesterol level of LDL along
with the much high prevalence of the retinopathy as well that is 0.11 as
compared to the ones having late onset of this diabetes. Patients having this
diabetes 2 in china with the early start of this disease have much high risk of
the non-fatal disease that is related to the cardiovascular as compared to the
patients having late onset of this disease diabetes type 2. (Pan, 2009)
Results
have also showed that diagnosis of this Diabetes type 2 in the china is still
facing number of different kind of challenges. Very first thing is, fasting of
the plasma glucose along with the oral glucose tolerance test requires that
patient to do the fasting process for maximum of 8 hours which ultimately
reduces the chances for the diagnosis of diabetes type 2 in the patient. Second
one is, as HbA1c cut off the certain points and they also vary on the terms of
ethnic group, gender, age group along with the prevalence of diabetes. For
this, particular diagnostic values need to be established. (Pan X. R., 1997)
It
has also been found out that the ratio of diabetes type 2 is increasing
globally but in china it is increasing more rapidly as compared to any other
country. It has been found out that back in 2000, number of the diabetes was
almost 151 million globally. Then in 2009 it was almost 88% and that makes
almost 285 million. Increase of this diseases was also being observed back in
2011 and it was found out to be 366 million and then in 2013 it was 382
million. Then in 2017 it was 425 million. On the basis of present research,
estimation has been done and it has been found out that it has been estimated
that in 2013, ratio will increase to 578 million in the future times if things
don’t become under control. (Wang, 2017)
Diabetes
in china has been generalized into three different kind of the groups Type 1
Diabetes, Type 2 Diabetes and the Gestational diabetes. Apart from them there
are some of other common type of the diabetes are also known in china and rest
of the world as well by the name of monogenic diabetes and then the secondary
diabetes. China has been reported to have the largest prevalence of Diabetes in
the whole globe by reporting the percentage of 1.67% back in 1980 and the
percentage has been increased drastically since then and back in 2010 it was
reported to have 11.6%. (Wang W. M., 2009)
Results
shows that prediabetes was known to be at the ratio of 35.7% in the china and
in them the higher prevalence was of the obese people or individuals. Then in
another study, prevalence of diabetes estimated to be 60% and the patients were
of middle and the elder age and this ratio was found between 2011 and 2012. The
same study established an increasing trend of diabetic patients to be
influenced by the age factor. Prevalence of diabetes increase in cases
involving high body mass index, larger waist circumference and fasting
cholesterol. (Weng, 2016)
It
has been found out that there are many people in the whole globe and especially
in china as well who are suffering from this Diabetes type 2 and apart from
them, many of them are still at the stake of having this Diabetes type 2 due to
number of different reasons that has been known and the reasons include:
Lacking in physical activity along
with inappropriate diet:
Physical activity:
Physical
activity makes every individual active enough and they feel physically fit.
Chances become half that any disease comes even near to them. Unfortunately as
we all know that our physical activity has been reduced due to the overuse of
social media and our busy life. One should always remain indulge in the
physical activity to make them physically fit and strong because this is
another way through which an individual can stay safe from the diabetes type 2
along with many other diseases as well. (Wong, 2006)
Health
factors and the behavior can help in the protection against the developing
diabetes while others can also increase the risk of a person of developing this
condition. Changes in the lifestyle like losing weight, eating healthy food and
increasing the physical activity are all considered to be the protective
factors and helps in reducing the risk of diabetes to take place in a person.
Another evidence has also been known and that is breastfeeding helps in
reducing the risk of maternal type 2 diabetes in the later stages.
Risk
factors associated with diabetes 2 can further be divided into two categories,
modifiable means that can be changed and non-modifiable that can’t be changed.
Non-modifiable factors are the ones that includes the family history and age of
the person. Modifiable factors that increase the risk of developing this
diabetes disease especially diabetes 2 and it may include:
• High level of blood cholesterol: Low
amount of the cholesterol in the body is continuously related towards the
increased risk of the diabetes type 2. Low level of cholesterol along with the
high amount of triglycerides are considered to be the part of diabetes in the
people. Number of different studies and experiments have shown that high amount
of the cholesterol in the blood contribute towards the pathophysiology of the
diabetes type 2 by effecting directly on the levels of plasma glucose. The
cholesterol amount further activates the secretion of pancreatic B-cell along
with the modulates glucose.
• High level of blood pressure: It is
commonly though that may be only high blood pressure would only lead to heart
attack and people just take care of that part but they completely forget about
another disease that is very common in the blood pressure patients and that is
Diabetes type 2. Blood pressure is commonly found in almost every second person
in the population of any area. People having blood pressure have an increased
risk of diabetes type 2 and the ratio of people who are at the risk are almost
50% out of 100% in every area. Common cause of high level of blood pressure is
the high amount of the salt in diet so, it is better to avoid taking the
excessive amount of salt in diet to reduce the risk of blood pressure along
with diabetes type 2 as well.
• Tobacco smoking: Back in 2014, it was
found that smoking is one of the major cause of diabetes type 2. In other words
it is also known as adult-onset diabetes. Smokers have much high risk for the
development of diabetes type 2 as compared to the nonsmokers. Chances of
developing this diabetes type 2 starts getting to increase with the amount of
cigarettes one smokes each day. To avoid this diabetes type 2, its better for a
person to quit smoking as soon as possible.
• Low levels of the physical activities:
When a person stops doing physical activity and that activity can be of any
type, it further leads to the diabetes type 2 in the people. Weight loss that
takes place from increased level of physical activity help out the different
muscle cells to use the insulin along with glucose more effectively, therefore
it lowers down the risk of diabetes. Lack of exercise further leads the muscle
cells to lose the sensitivity for the insulin which further helps in
controlling the amount of sugar in the body of a person.
• Obesity or being overweight: Being
overweight or obese further increases the chances for developing the diabetes
type 2 in people. Here in this disease, body do makes enough of the insulin but
different cells in the body become completely resistant for the salutary action
of an insulin because of the overweight. This starts ranging from environment
and then to the deep dark recesses for the single cell. A person becomes obese
due to number of different reasons like eating junk food in excessive amount,
lying all day in the couch without doing anything and things like these. So,
obesity is the biggest reason to cause diabetes type 2 in people.
• Poor diet and not eating healthy food:
Poor diet here means a diet that is very much high in calories, fats and this
further leads to the cholesterol increase in a person and in result the risk of
diabetes also increases. This poor diet leads a person towards obesity that
itself is another risk of diabetes type 2 as mentioned above, along with many
other health problems or issues as well. To avoid this diabetes type 2, person
should start eating healthy food to lead a healthy life and this healthy food
means, diet that is high in fiber and low in the cholesterol level, fats, sugar
and salt as well.
Increasing Obesity: Obesity
or being overweight is directly associated with the cause of diabetes type 2 in
people. And this is not necessary at all that only aged people or people above
30 years can have the chances of this diabetes type 2 disease if they are fat.
You are completely thinking wrong here, young people who don’t control their
weight and become obese are also at the stake of having this diabetes type 2. A
person becomes obese by eating a long of sugary food, means food that is high
in the sugar level like eating desserts, chocolates and candies. Obviously
increased amount of sugar in diet leads to diabetes and obesity both. Then
eating junk food like burgers, pizza and fizzy drinks are the other cause of
making a person obese. So, to avoid diabetes type 2 along with many other
health problems, it is really important for a person to start eating healthy
food.
In
approximately, 95% of the patients with diabetes in the china have Diabetes
type 2, this rapid increase in the occurrence of this disease in the china may
attribute towards the increasing rates of the obesity and being overweight
along with the reduction in physical activity that is being driven by the
economic development, lifestyle along with the diet which they take. According
to the surveys being conducted, the occurrence of overweight in the adults of
china having age of 20-59 increased from 37.4% in 2000, then 39.2% in 2005,
4.7% in 2010 and then 41.2% back in year 2014 and the estimate increase is 0.2%
each year. The rate of obesity also increasing in the population of china. (Yang, 2010) (Zhou, 2013)
Conclusion on Number of
different articles were being reviewed here in this study:
Diabetes
mellitus is a disease in which body becomes unable to use the energy properly
while after eating any type of the food. There can be two situations for having
this disease:
Pancreas
is an organ which is situated behind the stomach in the body which produces
small amount of insulin or no insulin. Insulin is a hormone which is being
produced naturally by the beta cells which are present in the pancreas and this
hormone further helps the body to use sugar for the sake of energy. Without
energy body can’t move.
Or,
pancreas as already talked that it is responsible in the production of insulin
but this hormone fails to work as it does in normal bodies. This is a condition
which is known as insulin resistance.
In
the process, sugar also leaves the bloodstream and then enters into the cells
and the level of blood sugar gets low. Without having proper amount of insulin
or the key sugar becomes unable to get into the cells of body for the use of
energy. All this process results into the rise in sugar level. Certain amount
of sugar is acceptable in the body, extra amount of sugar in the blood is not
good at all and can cause a disease which is known as Hyperglycemia which means
high amount of sugar in the blood or in simple words it can also be termed as
Diabetes. Diabetes 2 is deadly disease, can take your life easily. Number of
different people died because of it only because of their carelessness. This
disease took the life of many young and old men as well as women. Many
miscarriages have also been faced because of this disease. Rather than waiting
for all the symptoms to get appear it’s better to consult a doctor as soon as
possible to know about the type. As soon as it gets diagnosed it becomes much
easy to get it treated. Make sure to take its treatment on time rather than
skipping injections or medicine or what so ever recommended by your doctor.
Diet should be controlled along with the weight. Awareness of this disease
should be spread to make people know about its effects Life is precious gift of
nature and should be treated with care. Negligence in diagnosis cause troubles
in the later life. We should as a society stand up and make the society
healthier before it gets too late. This report has given all of the basic
information that a diabetic 2 patient needs to have to make their life better
and recover soon as well. Along with all this I would also like to say that
every person whose family history have this disease of Diabetes 2 need to be
very careful because it is an inherited disease and the chances for them also
increases double times. So to take precautions for Diabetes 2 when they get to
have this disease, it’s much better to control diet and maintain a healthy life
style by doing physical activities to make sure Diabetes 2 won’t affect you at
all. Stay safe by maintaining a healthy lifestyle.
Filters
|
Inclusion
|
Exclusion
|
Standards
of medical care for type 2 diabetes in China 2019. Diabetes/metabolism
research and reviews.
|
Causes
of type 2 diabetes in China. The Lancet Diabetes & Endocrinology.
|
Diagnosis
and classification of diabetes mellitus
|
Efficacy
and safety of sitagliptin in the treatment of patients with type 2 diabetes
in China, India, and Korea. Diabetes research and clinical practice,
|
Type
2 diabetes mellitus in China: a preventable economic burden.
|
Gestational
diabetes mellitus. Diabetes care, 27,
|
Prevalence
and ethnic pattern of diabetes and prediabetes in China in 2013. Jama,
|
Prevalence
of diabetes among men and women in China.
|
Type
I diabetes mellitus. New England journal of medicine,
|
NHG-Standaard
Diabetes mellitus type 2. In NHG-Standaarden 2009
|
Frequency,
immunogenetics, and clinical characteristics of latent autoimmune diabetes in
China
|
Gestational
diabetes mellitus. The Journal of clinical investigation,
|
|
Prevalence
of diabetes and its risk factors in China,
|
Diabetes
mellitus and hypertension. Hypertension,
|
Table
References of Number of
different articles were being reviewed here in this study:
Jia, W. W. (2019). Standards of medical care for
type 2 diabetes in China 2019. Diabetes/metabolism research and reviews.,
35(6).
Ma, R. C. (2014). Causes of type 2 diabetes in China. The
Lancet Diabetes & Endocrinology. 2(12), 980-991.
Mohan, V. Y. (2009). Efficacy and safety of sitagliptin in
the treatment of patients with type 2 diabetes in China, India, and Korea.
Diabetes research and clinical practice,. 83(1), 106-116.
Pan, C. Y. (2009). Management of Chinese patients with type
2 diabetes, 1998–2006: the Diabcare-China surveys. Current medical
research and opinion,, 25(1), 39-45.
Pan, X. R. (1997). Prevalence of diabetes and its risk
factors in China, 1994. Diabetes care,. 20(11), 1664-1669.
Wang, L. G. (2017). Prevalence and ethnic pattern of
diabetes and prediabetes in China in 2013. Jama,. 317(24), 2515-2523.
Wang, W. M. (2009). Type 2 diabetes mellitus in China: a
preventable economic burden. The American journal of managed care,, 15(9),
593-601.
Weng, J. (2016). Standards of care for type 2 diabetes in
China. Diabetes/metabolism research and reviews,. 32(5), 442-458.
Wong, K. C. (2006). Prevalence of type 2 diabetes mellitus
of Chinese populations in Mainland China, Hong Kong, and Taiwan. Diabetes
research and clinical practice,,, 73(2), 126-134.
Yang, W. L. (2010). Prevalence of diabetes among men and
women in China. New England journal of medicine,, 362(12), 1090-1101.
Zhou, Z. X. (2013). Frequency, immunogenetics, and clinical
characteristics of latent autoimmune diabetes in China (LADA China study): a
nationwide, multicenter, clinic-based cross-sectional study. Diabetes,. 62(2),
543-550.