Loading...

Messages

Proposals

Stuck in your homework and missing deadline? Get urgent help in $10/Page with 24 hours deadline

Get Urgent Writing Help In Your Essays, Assignments, Homeworks, Dissertation, Thesis Or Coursework & Achieve A+ Grades.

Privacy Guaranteed - 100% Plagiarism Free Writing - Free Turnitin Report - Professional And Experienced Writers - 24/7 Online Support

A sickeningly sweet baby boy

25/03/2021 Client: saad24vbs Deadline: 3 days

Lab 9: Follow the instructions and complete the assignment below. Submit your answers through the Lab 9 submission on Blackboard.

Lab 9 1

Lab 9. Inheritance 2

In this lab, we’ll be exploring inheritance again, but in humans. First, we’ll be looking at a real- life scenario of a known human disorder, and work through the family history to understand how the disorder works. Second, we’ll be exploring your own facial traits and seeing how inheritance works with a partner of your choice. EXERCISE 1 For this exercise, you’ll be exploring a real life scenario on inheritance in humans. A. Read the scenario below: A Sickeningly Sweet Baby Boy: A Case Study on Autosomal Recessive Inheritance by Jacqueline Washington, Department of Biology and Chemistry, Nyack College, Nyack, NY Anne Zayaitz, Department of Biology, Kutztown University, Kutztown, PA

Scenario: Emma and Jacob Miller were so excited at the birth of their baby Matthew.

Both the pregnancy and delivery had been uneventful. But in the back of their minds, they really were worried because their first child, Samuel, died at the age of nine days. By the fifth day after birth, Matthew began to have trouble nursing and by the seventh day he had completely stopped feeding. Emma and Jacob were frantic because it seemed to them that Matthew might also die. “What is going on with our family? Another sick baby?” Jacob thought to himself.

Emma and Jacob rushed him to the emergency room. Although Mathew’s limbs were rigid and he had had a seizure, the examination showed no infection and his x-rays were normal. The doctor also did routine lab tests on his blood and urine. “Doctor, do you think that this funny smell in Matthew’s diapers has anything to do with his problem?” Emma asked. “I brought one along so that you could smell it too.”

Matthew’s urine did have a sweet, maple syrup smell and lab results revealed elevated levels of the branched chain amino acids valine, isoleucine, and leucine. Skin biopsies from the baby and his parents were taken and cultured. The ability of the cultured skin fibroblasts to metabolize these three amino acids was determined. While his parents’ enzyme activity levels were nearly normal, Matthew’s was 200 times lower than normal.

“Given the medical information and the smell of the urine, Matthew has Maple Syrup Urine Disease (msud),” reported Dr. Morton of the Clinic for Special Children. “He will not be able to breast feed or drink regular formula. What is really important is that Matthew eats a low protein diet. This diet must continue for the rest of his life or else the amino acids will accumulate in the body creating a situation that leads to brain swelling, neurological damage, and death. In spite of dietary intervention, the disease may cause several complications, the most notable being mental retardation.”

Lab 9: Follow the instructions and complete the assignment below. Submit your answers through the Lab 9 submission on Blackboard.

Lab 9 2

A discussion with Emma’s grandmother revealed that Emma’s mother had two sisters who died in their first year of life; no one knew why. Jacob’s father had a brother who died at seven months of age from unknown causes. Could the gene for msud run in both of their families?

msud is due to a recessive gene. For an individual to be affected, he or she would need to inherit a defective nonworking copy from each parent. The individual would then be described as being homozygous recessive.

B. Now that you’ve read the scenario, we are going to build a genetic pedigree (a family tree) with the information from the scenario above. There are a few “conventions” on drawing pedigrees: women are depicted as circles, men as squares. If individuals are affected by a conditions, their circle/square gets filled in. When two individuals have children, they are linked by a line, with their children located below the line, all connected. As such, you can see generations forming in the pedigree, from oldest at the top to youngest at the bottom. An example pedigree is provided here for a hypothetical family, with all the kids and grandkids that resulted from one couple:

Now that we’ve seen how pedigrees are built, build your pedigree for the scenario that includes:

Emma Jacob’s mother Jacob Jacob’s father Matthew Emma’s deceased aunts Samuel Jacob’s deceased uncle Emma’s mother Emma’s father

C. Using the letter M for normal metabolism and m for msud, fill in the genotypes on your family tree for as many individuals as you can. If you know one allele, but not the other, use a dash in place of the unknown allele, e.g. M_ Now that you’re done, answer the following questions:

Lab 9: Follow the instructions and complete the assignment below. Submit your answers through the Lab 9 submission on Blackboard.

Lab 9 3

1. What are the phenotypes of Emma and Jacob for our gene of interest? What are their genotypes? 2. How could Emma and Jacob’s son have inherited msud even though neither parent suffers from msud? 3. Using the pedigree you drew from this scenario, how many individuals have had msud in this family? How many were most likely carriers? Justify your answers by explaining the logic of your pedigree. 4. What is the probability that Emma and Jacob’s next child would have msud? Justify your answer. If you were Emma and Jacob, now that you know the probability, would you have another child? Explain your answer briefly 5. Did you enjoy this exercise? Why or why not? Compare it to the 2 other exercises you did in Lab 8: is there one exercise that helped your learning on inheritance more than another? Explain briefly.

EXERCISE 2:

This activity can only be completed in pairs – your pair member can be anybody you’d like (your roommate, coworker, best friend, sibling over the phone, etc). A. Determine your personal genetic profile: work with one partner and determine your phenotype based on the characters illustrated in the figures (provided at the end of this homework). Determine the genetic basis of the phenotype when possible—for example, if you have blue eyes, then you know that the genotype for that phenotype is recessive (2 recessive alleles). If you have brown eyes, then you can only know for sure that you have 1 allele for brown eyes—the other allele could be for either brown or blue eye color. Fill out Table 1 (located at the end of this homework). To avoid confusions, I’ve completed the first few lines of that table for myself and my husband as an example to show you what it should look like…

Homework is Completed By:

Writer Writer Name Amount Client Comments & Rating
Instant Homework Helper

ONLINE

Instant Homework Helper

$36

She helped me in last minute in a very reasonable price. She is a lifesaver, I got A+ grade in my homework, I will surely hire her again for my next assignments, Thumbs Up!

Order & Get This Solution Within 3 Hours in $25/Page

Custom Original Solution And Get A+ Grades

  • 100% Plagiarism Free
  • Proper APA/MLA/Harvard Referencing
  • Delivery in 3 Hours After Placing Order
  • Free Turnitin Report
  • Unlimited Revisions
  • Privacy Guaranteed

Order & Get This Solution Within 6 Hours in $20/Page

Custom Original Solution And Get A+ Grades

  • 100% Plagiarism Free
  • Proper APA/MLA/Harvard Referencing
  • Delivery in 6 Hours After Placing Order
  • Free Turnitin Report
  • Unlimited Revisions
  • Privacy Guaranteed

Order & Get This Solution Within 12 Hours in $15/Page

Custom Original Solution And Get A+ Grades

  • 100% Plagiarism Free
  • Proper APA/MLA/Harvard Referencing
  • Delivery in 12 Hours After Placing Order
  • Free Turnitin Report
  • Unlimited Revisions
  • Privacy Guaranteed

6 writers have sent their proposals to do this homework:

Smart Tutor
Writing Factory
Engineering Help
Engineering Exam Guru
Assignment Hub
Essay Writing Help
Writer Writer Name Offer Chat
Smart Tutor

ONLINE

Smart Tutor

I will cover all the points which you have mentioned in your project details.

$69 Chat With Writer
Writing Factory

ONLINE

Writing Factory

I am known as Unrivaled Quality, Written to Standard, providing Plagiarism-free woork, and Always on Time

$28 Chat With Writer
Engineering Help

ONLINE

Engineering Help

I have read and understood all your initial requirements, and I am very professional in this task.

$46 Chat With Writer
Engineering Exam Guru

ONLINE

Engineering Exam Guru

Give me a chance, i will do this with my best efforts

$23 Chat With Writer
Assignment Hub

ONLINE

Assignment Hub

I will cover all the points which you have mentioned in your project details.

$59 Chat With Writer
Essay Writing Help

ONLINE

Essay Writing Help

Hello, I an ranked top 10 freelancers in academic and contents writing. I can write and updated your personal statement with great quality and free of plagiarism

$48 Chat With Writer

Let our expert academic writers to help you in achieving a+ grades in your homework, assignment, quiz or exam.

Similar Homework Questions

Winter vs summer essay - The strategy of Plan, Do, Check, and Act - One major avenues for achieving a cost advantage over rivals is by - Behavior modification project papers - Integers and absolute value powerpoint - How to convert spss tables into word - How to calculate outright quotes for bid and ask - Discussion - What is a 10 51 police code - Nanda nursing diagnosis for necrotizing enterocolitis - Radiant tube heater layout - List of irregular past tense verbs in spanish - Hum 100 project 1 artifact chart - Biology - Flipkart ebay merger case study - Anzca primary exam curriculum - Walter cunningham sr quotes - Administration and Supervision in Criminal Justice - Chapter 6 - Jireh international pty ltd - Unisex Asymmetrical Dark Blue Biker Leather Jacket - Uxbridge middlesex ub8 3ph - Briefly describe how supportive and interpersonal psychotherapies are similar - Nasa postdoctoral program success rate - Dna replication and protein synthesis crossword answers - William shakespeare thesis statement - How does katniss plan to strike at the careers - Wilhelm schickard calculating clock - HCA320 Assignment Mod 5: - Quartz crystal microbalance price - Stakeholders (Internal & External) - Psychology assignment: My Disease Risk Factors - Solver paint colours chart - Which one of the following accounts is the most liquid - Solutions to exercises in introduction to logic irving copi - Challenges - Introduction to Philosophy EXAM 1 - Disadvantages of budgeting process - Fat twins alice in wonderland - Evaluation of ncf 2005 - Admin Discussion Board - 25 abbey street leura - Warranty expense classification on income statement - NURS-6050N-66/NURS-6050C-66-Policy & Advocacy - 3538 pear blossom circle oceanside ca - Independent t test spss - Procoptodon goliah modern relatives - Downey sda church children's story - Martin brundle mercedes 190e cosworth - Windshield urvey form - CONCEPT APPLICATION: LULULEMON: FOR THE LOVE OF YOGA - What is the name of this compound - Short student council speeches - Camp millowski excel - English studies in india - Samples of anecdotal observations in childcare - The physiological effects of pornography on the brain - Route 121 bus schedule - How loud is 6 sones - Closing net assets drawings capital introduced opening net assets - Sorority social media rules - An example of a committed fixed cost is - Organic chemistry 1 review - Over voltage protection pdf - I'm trading my sorrows lyrics - Bsbmgt502 task 1 answers - Cover page group assignment - Disadvantages of written communication - Inhaler technique geeky medics - When i consider how my life is spent - Occurrence and extraction of aluminium - Lab 3 biodiversity answers - Create A Question - Hot hand fallacy economics - Shakespeare in the bush - Iso 9001 risk matrix - What is an acceptable safeassign score - Ion boardroom theme word 2016 - Bikini body workout plan pdf - Discussion - Whippers pizza augusta maine menu - Western michigan university sociology - Ibm co marketing center - When did cubism start - Help - Outline Paper - M management bateman 4th edition pdf - Run lola run quotes at beginning - Individual Project(2 different copies needed) - Intercompany profit transactions inventories - Explain marketing myopia - Hcf ambulance only cover - 2parts - Find the slope of the tangent line to the ellipse - Glo bus quiz one answers - Study Questions and Essays - Migi-hidari artist of the floating world - Analyzing managerial decisions interwest healthcare corp - Which of these is an example of verbal irony - Pop art title page - Application of health promotion model in nursing