Adavanced Patho.

Altered Physiology

the case study analysis scenario

A 42-year-old man comes to clinic with chief complaint of pain, redness, and swelling of his right calf. He states that he had been working in his yard using a string trimmer when the trimmer slipped and cut his leg. He cleaned the wound with water from the garden hose and covered the wound with a large Band-Aid. Several days later, he developed fever to 100.6˚ F and chills and noticed that his leg was swollen and red. He comes to the emergency department for definitive care.

The Assignment (2-pages case study analysis)

Develop a 2-page case study analysis in which you:

· Explain why you think the patient presented the symptoms described.

· Identify the genes that may be associated with the development of the disease.

· Explain the process of immunosuppression and the effect it has on body systems.

3 citations APA Format 7th Edition. 

Include a title page, introduction, summary, and references. 

In developing your discussion posts, I will encourage you to think about cellular pathophysiology. I always want to know what is happening in the cells that produce the clinical manifestations of the disease.

Your post will be stronger if you do not cite patient educational sites such as WebMD, Mayo clinic Healthline etc. To this end, Wikipedia is never acceptable as an academic source. You will see point deductions if you cite these sources in your posts and paper. 

Required Reading

McCance, K. L. & Huether, S. E. (2019). Pathophysiology: The biologic basis for disease in adults and children (8th ed.). St. Louis, MO: Mosby/Elsevier.

·  Chapter 1: Cellular Biology; Summary Review

·  Chapter 2: Altered Cellular and Tissue Biology: Environmental Agents(pp. 46-61; begin again with Manifestations of Cellular Injury pp. 83-97); Summary Review

· Chapter 3: The Cellular Environment: Fluids and Electrolytes, Acids, and Bases,

· Chapter 4: Genes and Genetic Diseases (stop at Elements of formal genetics); Summary Review

· Chapter 5: Genes, Environment-Lifestyle, and Common Diseases (stop at Genetics of common diseases); Summary Review

· Chapter 7: Innate Immunity: Inflammation and Wound Healing

· Chapter 8: Adaptive Immunity (stop at Generation of clonal diversity); Summary Review

· Chapter 9: Alterations in Immunity and Inflammation (stop at Deficiencies in immunity); Summary Review

· Chapter 10: Infection (stop at Infectious parasites and protozoans); (start at HIV); Summary Review

· Chapter 11: Stress and Disease (stop at Stress, illness & coping); Summary Review

· Chapter 12: Cancer Biology (stop at Resistance to destruction); Summary Review

· Chapter 13: Cancer Epidemiology (stop at Environmental-Lifestyle factors); Summary Review 

Justiz-Vaillant, A. A., & Zito, P. M. (2019). Immediate hypersensitivity reactions. In StatPearls. Treasure Island, FL: StatPearls Publishing. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK51