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Hi, I have a question related to enzyme kinetics.
If a person has consumed 50 ml methanol (a lethal dose), calculate how much absolute (100%) ethanol this person would have to consume to reduce the reaction rate Vo to 3% of the original value.
The KM for the oxidation of methanol by ADH is 0.01 M and KI for ethanol as inhibitor for this reaction is 0.001 M. Assume that the total fluid volume in the person’s body is 38 litres. The densities of ethanol and methanol are 0.789 g/ml and 0.791 g/ml, respectively. Assume Michaelis Menten kinetics for the reaction. (13 Marks)
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