Part 1:
Directions: Explore the attached article and videos. Answer the associated questions with a few short sentences. Each question is worth 1 point unless otherwise noted for a total of 35 points. Please submit under the “journals” tab under the heading “DNA: Gene therapy and cloning”.
DNA : Gene therapy and cloning
Directions: Explore the attached article and videos below. Answer the associated questions with a few short sentences. Each question is worth 1 point unless otherwise noted for a total of 35 points. Please submit under the “journals” tab under the heading “DNA: Gene therapy and cloning”.
Picture courtesy of http://img.timeinc.net/time/2001/stemcells/images/stemcells.jpg
What are the ethical issues surrounding the stem cell debate?
“Human embryonic stem cell (HESC) research offers much hope for alleviating the human suffering brought on by the ravages of disease and injury. HESCs are characterized by their capacity for self-renewal and their ability to differentiate into all types of cells of the body. The main goal of HESC research is to identify the mechanisms that govern cell differentiation and to turn HESCs into specific cell types that can be used for treating debilitating and life-threatening diseases and injuries….”
(#1) Ethics of Stem Cell Research: http://plato.stanford.edu/entries/stem-cells/ (5 points)
1. The standard view of those that oppose Human Stem Cell Research is that a human being begins to exist with the emergence of what?
2. Why do Smith and Brogard (2003) and McMahan (2002) reject the stipulation that the early human embryo is a human being?
3. What are some of the capacities that are necessary for the right to Life?
4. How does the article morally distinguish the creation of embryos for reproductive purposes from the creation of embryos for research and therapeutic reasons? (2 points)
(#2) The Ethical Questions of Stem Cell Research (6 minutes) (4 points)
https://www.youtube.com/watch?v=f5d0ieWfKlI
1. What were the first guidelines available in the United States for governing the use of stem cells in research?
2. What is the Hinxton group?
3. Under the National Academy of Science, What does ESCROC stand for?
4. Who is involved in ESCROC?
What is the technology behind our understanding of gene transfer and cloning?
http://www.intechopen.com/source/html/44748/media/image4.jpeg Image result for clones
Pictures courtesy of: http://www.wnd.com/files/2012/12/babies-cloning-340x255.jpg
http://www.intechopen.com/source/html/44748/media/image4.jpeg
(#3)Eyes of Nye: Cloning (24 minutes) (11 points)
http://www.bing.com/videos/search?q=eyes+of+nye+cloning&&view=detail&mid=80D719E65E993F03C22880D719E65E993F03C228&FORM=VRDGAR
1. What are some of the benefits to therapeutic cloning?
2. Describe the process of somatic cell nuclear transfer. (2 points)
3. The first patent for cloning was given to the scientists who cloned Dolly the sheep. What did this provide for the company?
4. Dr. Billie Swalla uses stem cell research to study how genes do what?
5. Why does reproductive cloning not work very well?
6. Dolly died at the age of 7 indicating what about the nucleus used?
7. Dr. Hans Keirstead works with human embryonic stem cells in hopes of treating what kinds of injuries?
8. What evidence is shown (with the rats) that human embryonic stem cells have great therapeutic hope for the future?
9. What is happening inside the rat with the injected stem cells?
10. Where does Dr. Jeffery Kahn stand with regard to moral rights of the embryo?
11. Is there a law in the United States that prohibits that prohibits cloning?
(#4) Stem Cells- The Future: An Introduction to iPS cells (16 minutes) (5 points)
http://www.bing.com/videos/search?q=stem+cells+the+future+videos&FORM=HDRSC3#view=detail&mid=42240DF444901218969542240DF4449012189695
1. What are some of the benefits for using iPS cells? (2 points)
2. What types of patients does Dr. Shinyayamanaka hope to help with his technology?
3. What are the new ethical questions that arise with this technology? (2 points)
http://img2.timeinc.net/people/i/2007/archive/covers/95/6_12_95_205x273.jpg https://kinoimages.files.wordpress.com/2012/06/christopherreeve-herb-ritts.jpg
Images courtesy of: http://img2.timeinc.net/people/i/2007/archive/covers/95/6_12_95_205x273.jpg https://kinoimages.files.wordpress.com/2012/06/christopherreeve-herb-ritts.jpg
(#5) Cloning Humans? – (30 minutes) (10 points)
https://www.youtube.com/watch?v=R4JoRy_vNEw
1. What is the difference between reproductive cloning and therapeutic cloning?
2. The Eugenics movement in the first part of the 20th century resulted in sterilization of certain members of the population whose genes were determined to not be desirable. How is cloning related to this movement? (3 points)
3. Dr. Brent Blackwelder (President of “Friends of the Earth”) claims that genetic engineering will be similar to “invasive species” which could harm the environment. True or false?
4. According to the video, before researchers can use cloning in their research they must do what (in the code of practice)?
5. What was the cloning scandal that occurred in Korea?