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Below is the Retrosynthetic analysis of a potential antiretroviral drug for HIV from an Organic Letters article. Answer the following questions related to this retrosynthetic analysis. For the retrosynthetic disconnection of D to E, draw out the best pair of synthons. For the retrosynthesis of A to B + C, label the carbons of structure A with numbers and then use the same numbers to label the corresponding carbons of structures B and C. Draw a retrosynthesis corresponding to the following synthesis. Indicate the organic synthons for each step as well as the actual organic reactants. Be sure to show each disconnection and use appropriate symbols as shown in class.
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