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Engineering Physiology I (BME 301) Homework #3 Assigned: October 21, 2019 Due: October 28, 2019 For the circuit shown below describing ion flux in a plasma membrane, state what each circuit element represents in a cell. Write a MATLAB code to simulate action potential generated in a cell membrane when subjected to impulse stimulus as per Hodgkin-Huxley model. 1. Plot voltage across membrane vs time. Explain how the plot represents action potential. 2. Plot total conductance of sodium and total conductance of potassium channels vs. time (two plots on same graph). Explain the trend with respect to action potential and working of voltage gated channels. 3. Plot m, h and n vs. time. What do m, h and n represent? Explain the results and how the result corresponds to Na and K voltage gated channel’s activity during action potential? How the time constants of the m, n and h curve correspond to the slow and fast acting voltage gated channels? 4. Why gL does not have a gate constant? Submit the MATLAB code, plots with appropriate labels. ...
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