Microbiology case studies and answers

CASE STUDY RUBRIC MICROBIOLOGY The current pathogen selections include the following (select only one for your Case Study from the list). Be sure to read the rubric carefully as it is very helpful.  Aeromonas hydrophila  Balamuthia mandrillaris  Borrelia recurrentis  Burkholderia pseudomallei  Clonorchis sinensis  Ebola virus  Extensively drug-resistant TB, XDR-TB  Fusarium incamatum-equiseti or Bipolaris hawaiiensis  Leishmaniasis  Middle East respiratory syndrome coronavirus (MERS-CoV)  Yellow fever virus  Zika virus Assigned Case Study Problem: You will create a case study for a microbial infection selected from the current pathogen list. Your case study will be assembled using a detailed rubric (see below). Upon completion, and by a specified due date (within Unit 5), your case study will be submitted using the Blackboard website. How to create a case study The case studies are meant to be an enjoyable, interesting, and informative assignment. This is your chance to show that you understand the key teaching points about a microbe and to communicate these points to in a written format. Have at least 3-4 key referenced points in each of the five areas. The chart below suggests the type of information requested for the pathogen. Outlines can be in whatever form you prefer (bullets/charts/outlines/diagrams or a mix). Be sure to include two discussion questions (and provide complete answers) that you can incorporate into your case study (place them at the end of your write-up). These questions should help connect your case to other material in the course. For example, what other microbes have an A-B toxin? What other viruses are transmitted by fecal-oral spread? Pertinent references can be listed at the bottom of your outline in a small font. Use American Medical Association Manual (AMA) Style format for all references. Your textbook may be listed as “Microbiology: A Human Perspective Eugene W. Nester et.al. McGraw-Hill Publisher 7th edition/ 2012”. Typical Case Description of the infectious agent What does a typical case look like? Use the standard format for a patient presentation with chief complaint (CC), history of present illness (HPI), key physical exam details (PE), lab findings, signature signs, and any other important findings. If it is a bacterium, how is it classified? If it is a virus, what kind of nucleic acid does it have? Does it target specific cellular types (tropism)? Does it form a spore? Is it aerobic? Is it intracellular? Can it only be grown in a specific type of media? How is it distinguished from other members of the species? Does the pathogen have a significant history with humans or animals? CASE STUDY RUBRIC MICROBIOLOGY Epidemiology Pathogenesis Prophylaxis/Treatment What do you feel are the most important points about the epidemiology of the disease? Incidence? Portal of entry? Source? Is it a normal microbiota component in the human body? Does it only occur in certain populations or certain geographical areas? Is there a vector involved? What and who is the vector? Is it zoonotic? Does it appear seasonally? Are there currently any outbreaks of this pathogen? What is its ecological niche? Is there a reservoir? Are there currently any outbreaks or epidemics of disease from this pathogen? What is the range of diseases caused by the agent? What organs are affected? What symptoms might the patient have? What is the disease course? Will the patient recover? Are there any long-term sequelae of infection? Latency? Is there an antitoxin? Specific antibiotics or a class of antibiotics that are used? Is there a vaccine available? Is treatment curative? Does infection make you immune? Is this immunity life-long? Is there drug resistance? Are there novel treatments? Addenda 1. The written case presentations are submitted through Blackboard in Unit 5 of the course. When you reach Unit 5, be sure to e-mail your instructor to receive a list of the Case Study selections. 2. Please name the files in the following manner “Lastname Firstinitial CS Y”. For example, if I am submitting a Case Study on tularemia, I would name the case study file “Frisardi M CS tularemia”. This will ensure that you receive appropriate credit and that I will be able to find your Case Study document easily when grading. For the Case Study, you are asked to provide at least the information requested in the boxes. The boxed questions are suggestions for the minimum amount of information within each category.