Global Stroke Guidelines and Action Plan: A Road Map for Quality Stroke Care
PRehoSPitAl And eMeRgenCy CARe
Authors: Lindsay MP, Norrving B, Furie KL, Donnan G, Langhorne P, Davis S On Behalf of the Global Stroke Quality and Guidelines Advisory Committee, the Global Stroke Guidelines Working Group, and the Global Stroke Quality Working Group.
Global Stroke Services Guidelines and Action Plan: Achieving and Monitoring Quality Stroke Care 2
PrehosPital and emergency care
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PuRPoSe:
The WSO Roadmap to Delivering Quality Stroke Care is an implementation resource to accompany the WSO Global Stroke Services Guideline and Action Plan. This roadmap provides the framework for the implementation, monitoring and evaluation of stroke services globally.
It provides standardization and consistency for the selection of evidence-based recommendations, approaches to implementations in clinical practice, and the calculation of performance measures to create an environment of continuous quality improvement.
tARget AudienCe:
The roadmap is intended to guide local healthcare officials and stroke care clinical groups in establishing stroke systems of care and implementing as many of the defined components as possible throughout the stroke continuum of care. The focus of the roadmap is on the processes of care and impacts on patient outcomes. It is recognized that not all regions will be able to provide all elements of quality stroke care; therefore the recommendations and performance indicators take into account what should be possible within three levels of service access.
It can be used by local, regional, or country-level health authorities and service providers as a foundation for their own evaluation frameworks for stroke.
governments and funders should use these guidelines and action plan to review existing services, and identify service gaps. These groups could then prioritize gaps and look for solutions to improve access to services. Clinicians and other healthcare workers should use these guidelines and roadmap to scrutinize local care delivery, access to care and ongoing support to achieve recovery goals.
This roadmap will also provide valuable guidance to stroke programs under development, to help ensure that all key elements defined here are considered from the beginning of development.
FoRMAt:
The roadmap is organized along the continuum of care starting at the onset of a stroke event through the acute phase (emergency department and inpatient care), stroke rehabilitation, prevention of recurrent stroke and concludes with community reintegration and long term recovery.
Each section represents a part of the continuum and enables users to review and assess the structural elements and services available for stroke care; core evidence-based best practice recommendations related to processes of care that should be operational; and, a list of key quality indicators to monitor levels of care provided and impact on patient and economic outcomes.
how to uSe:
Users of this Roadmap should: 1. Review the sections relevant to their phase of stroke services; 2. Complete an assessment of current services and resources, current recommendations in place, and current data collection methods and access; then 3. develop an implementation plan to ensure that these core elements are optimized and additional elements added to improve the stroke services they provide.
iMPleMentAtion:
1. Hands-on hardcopy resource 2. electronic interactive app/resource where users can enter what elements they have available from a master check list and the program identifies current level, recommendations and performance measures.
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PrehosPital and emergency care
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PREHOSPITAL AND EMERGENCY CARE This section focuses on the first hours following stroke. This includes early stroke assessment, diagnosis
and management from the first onset of stroke symptoms through the first 24 to 48 hours, when the
patient becomes medically stable. The goals of care in this phase are to diagnose the type of stroke
(ischemic or hemorrhagic), and initiate time-sensitive treatments to minimize the impact of the stroke
and prevent further damage. Hyperacute stroke care ideally involves healthcare providers with expertise
in stroke care, and takes place in a clinic or emergency department, but may occur in other settings
based on resource and facility availability.
health Service Capacity for Stroke Care Checklists^
REGION: ORGANIZATION COMPLETING CHECKLIST: PRIMARY CONTACT PERSON:
SERVICE SCOPE: GOALS OF THIS ASSESSMENT/COMMENTS: To be completed by local group
Provincial/State/National Assessment
Regional/Local assessment
Large urban hospital with advanced stroke services (comprehensive stroke services)
Community hospitals with access to some stroke services
Community with health clinic as only health services available
Rural community with a visiting health worker
Please complete the following information to clearly identify the stroke services you are developing or assessing.
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A. Stroke Services and Resource Availability
Please review each of these lists and tick all services and resources that you currently have in place and available for providing stroke care. Once completed, review your responses to determine which category of stroke services you most closely fit into.
Minimum healthcare Services
essential Stroke Services (In addition to services listed under
Minimal stroke services)
Advanced Stroke Services (In addition to services listed under
Minimal and essential stroke services)
Care provided in local communities without coordination across defined geographic regions
No access to diagnostic services or hospital care for hyperacute stroke treatment
Very limited access to physicians • Provide assessment skill
development • Basic training in swallow
screens and dysphagia management; and in temperature management
Variable access to healthcare workers (nurses or lay workers)
• Basic training in swallow screens and dysphagia management; and in temperature management
Access to basic diagnostic services
• Laboratory blood test (CBC, electrolytes, urea, glucose, INR, PT)
• Electrocardiogram (12 lead) • Computed Tomography (CT)
scan brain and vasculature • Capability to do CT
Angiography (CTA) • Echocardiography • Doppler ultrasound • Holter monitors
Limited access to emergency medical services
• Training of ambulance crews to identify stroke signs using FAST mnemonic
• Work with ambulance systems to have stroke identified as a high priority transport emergency, in addition to trauma and obstetrical crises
Access to nurses and nursing assessment with stroke training
• Primary care settings • Acute care settings • Advanced practice nurses • Nurse practitioner
Access to physicians with stroke expertise ( although may not be stroke specialists)
• General/Family/Primary care physicians
• Neurologist • Neurosurgeon • Internists • Cardiologist • Geriatrician • Emergency Medicine • Intensivist • Access to stroke specialists
through telestroke modalities, and teleradiology
Access to acute thrombolysis with IV tPA
• Intravenous tPA (Alteplase)
Access to advanced diagnostic services
• Magnetic Resonance Imaging (MRI)
• Capability to do MR Angiography
• CT Perfusion scans • Prolonged ECG monitoring
devices
Access to physicians with stroke expertise in acute stroke care, stroke prevention and/or stroke rehabilitation
• Neurologist • Neurosurgeon • Internist • Neuroradiologist /
interventionalist • Geriatrician • Intensivist • Cardiologist • Emergency Medicine • General/Family/Primary care
physician • Program to develop and
maintain core competencies in stroke care
Access to additional acute interdisciplinary stroke team members
• Nurses • Nursing assistants • Pharmacist • Palliative Care team
Access to advanced interventions:
• Intravenous tPA (Alteplase) • Endovascular thrombectomy • Neurosurgery for
hemorrhagic stroke • Hemicraniectomy for
ischemic stroke • Acute inpatient stroke units • Products to reverse
coagulopathy
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Minimum healthcare Services
essential Stroke Services (In addition to services listed under
Minimal stroke services)
Advanced Stroke Services (In addition to services listed under
Minimal and essential stroke services)
Members of a interdisciplinary stroke team
• Physicians with stroke expertise
• Stroke Nurses • Nursing assistants • Pharmacist • Social worker/case manager • Palliative Care team • Physiotherapist • Occupational Therapist • Speech-Language Pathologist
Protocols for rapid evaluation and diagnosis of stroke patients
Patient and family education, skills training, and involvement in care planning
Discharge planning
Limited coordinated stroke care provided across geographically discrete regions
Stroke training programs for all levels of healthcare providers
Fully coordinated stroke care provided across geographically discrete regions
• Advanced stroke services rationalized to a smaller number of centres
• Stroke pathways that define movement of stroke patients across region to higher and lower levels of services as required
• Coordinated referral system • Provide telestroke
consultations to smaller and more rural; centres
• Ambulance bypass agreements in place
• Repatriation agreements in place to transfer patients back to home communities
• Printed stroke patient educational materials
Stroke training programs for all levels of healthcare providers
Data collection strategy and mechanisms
• Acute inpatient stroke registry • Acute inpatient stroke
database (local or regional) • Stroke prevention registry • Stroke prevention database • Stroke rehabilitation registry • Stroke rehabilitation database
(local or regional)
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health System and Stroke Recognition
Core evidence-Based Recommendations
Applicable level of health Services Capacity
for Stroke Care Supporting evidence Self Assessment
Minimum Essential Advanced
1. Onset of stroke symptoms should be obtained, documented and communicated to healthcare personnel
2. All patients with symptoms of stroke should be transported to a healthcare hospital that can provide organized stroke services.
3. All patients with focal neurological symptoms/ symptoms of stroke should receive brain imaging (CT scan or MRI) without delay.
4. Initial blood work should be performed
5. Electrocardiogram should be carried out in all patients, especially where the patient has a clinical history or evidence of heart disease or pulmonary disease.
6. All patients with stroke should have their swallowing function screened or assessed to determine possible dysphagia before offering food, drink or oral medications to patient.
7. All patients with acute ischemic stroke who can be treated within 4.5 hours of symptom onset should be evaluated without delay by a physician with stroke expertise (either on-site or by telemedicine/telestroke consultation) to determine their eligibility for treatment with intravenous tissue plasminogen activator (tPA)
Evidence level: C
Evidence level: B
Evidence level: B
Evidence level: B
In place In development Not implemented Not available
In place In development Not implemented Not available
In place In development Not implemented Not available
In place In development Not implemented Not available
In place In development Not implemented Not available
In place In development Not implemented Not available
In place In development Not implemented Not available
Evidence level: B
Evidence level: C
Evidence level: A
B. Core Stroke Care Recommendations
For each best practice recommendation, indicate with a tick whether the described practice is in place as a routine part of care; in development for implementation; not implemented, meaning the service/resource may be available but it is not currently part of stroke care within your services; or, the service/resource/equipment is not available within your facilities, therefore not possible to implement.
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health System and Stroke Recognition
Core evidence-Based Recommendations
Applicable level of health Services Capacity
for Stroke Care Supporting evidence Self Assessment
Minimum Essential Advanced
8. All patients with large vessel occlusion (LVO) and acute ischemic stroke (AIS) should be evaluated for endovascular thrombectomy where these interventions are available (onsite or through transfer to another stroke centre providing endovascular therapy).
Endovascular thrombectomy is now the standard of care for selected patients with acute ischemic stroke and large vessel occlusion presenting within 6 hours of stroke onset.
9. All acute ischemic stroke patients not already on an antiplatelet agent and who are not receiving alteplase should be given acetylsalicylic acid (ASA) immediately as a one- time loading dose (300 – 325 mg) followed by 75 – 150 mg per day after brain imaging has excluded intracranial hemorrhage.
10. Intracerebral hemorrhage should be promptly recognized and patients evaluated immediately by physicians with expertise in hyperacute stroke management
11. Patients with an acute stroke should be admitted to hospital.
12. Patients with minor stroke or transient ischemic attack should be urgently assessed and prevention management commenced, either in hospital or treated in a specialized outpatient clinic.
Evidence level: A
Evidence level: A
In place In development Not implemented Not available
In place In development Not implemented Not available
In place In development Not implemented Not available
In place In development Not implemented Not available
In place In development Not implemented Not available
Evidence level: C
Evidence level: B
Evidence level: A
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which recommendations are your highest priorities to implement?
what are your next steps to start development and implementation of these best practices?
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Performance Measures
hyperacute Stroke Care (First hours after stroke)
numerator denominator Self Assessment
1. Time from stroke onset to assessment by healthcare professional (in minutes/ hours).
2. Proportion of stroke and TIA patients who receive a CT scan within one hour of hospital arrival and within 24 hours of hospital arrival.
3. Proportion of stroke and TIA patients who are screened or assessed for swallowing deficits.
4. Proportion of ischemic stroke patients who are treated with intravenous tPA.
5. Door to needle time for ischemic stroke patients who receive tPA (minutes)
Median hour/minutes from Last Seen Normal time to Emergency Department arrival for all stroke and TIA patients
KQI2.a CT scan started (first slice) within 1 hour of hospital arrival (Yes/no)
KQ2.b CT scan started (first slice) within 24 hours of hospital arrival (Yes/ no)
Number of stroke/TIA cases with documentation of a swallow screening completed (No judgment about whether needed it or not, applicability or eligibility)
Number of all ischemic stroke patients who receive tPA (Alteplase).
Median time (in minutes) from patient arrival in the emergency department to administration of tPA for all patients who receive tPA for the treatment of acute strokeMedian (IQR)
Number of all ischemic stroke patients who undergo an endovascular thrombectomy.
Total number of stroke and/or TIA events in population. Or
Total number of ischemic stroke cases admitted to the ED or hospital (depending on local practices).
Total number of stroke and/or TIA events in population. Or
Total number of ischemic stroke cases admitted to the ED or hospital (depending on local practices).
Total number of stroke and/or TIA events in population. Or
Total number of ischemic stroke cases admitted to the ED or hospital (depending on local practices).
1. Total number of ischemic stroke cases admitted to the ED or hospital (depending on local practices).
2. Total number of ischemic stroke cases admitted to the ED or hospital (depending on local practices) who arrive within 4.5 hours of stroke symptom onset.
Total number of ischemic stroke cases admitted to the ED or hospital (depending on local practices). Total number of ischemic stroke cases admitted to the ED or hospital (depending on local practices).
Data collected In development Data not collected Data not available
Data collected In development Data not collected Data not available
Data collected In development Data not collected Data not available
Data collected In development Data not collected Data not available
Data collected In development Data not collected Data not available
C. Key Stroke Quality indicators
For each quality indicator, please note whether data is being actively and routinely collected; or, data collection processes are in development for the indicator; or, data may be available but it is not currently being collected; or, data for this indicator is not available at all so not able to collect or report it. Please tick the most appropriate box for each indicator.
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what indicators are priority for us?
who will collect the data?
how will the data be collected (electronically, on paper, etc)?
how will the data be analyzed? when? how often?
who will receive the results?
Performance Measures
hyperacute Stroke Care (First hours after stroke)
numerator denominator Self Assessment
6. Proportion of all ischemic stroke patients who receive acute endovascular therapy.
7. Median time from hospital arrival to arterial access (such as groin puncture) for patients undergoing endovascular therapy (minutes)
8. Proportion of ischemic stroke and TIA patients who receive acute aspirin therapy within the first 48 hours.
9. System indicator – availability of tPA
medication and endovascular services in region
Median time (in minutes) from patient arrival in the emergency department to arterial access (e.g., groin puncture) for all ischemic stroke patients who receive endovascular therapy.
Proportion of ischemic stroke and TIA patients who receive acute aspirin therapy within the first 48 hrs following symptom onset.
Proportion of all public/private healthcare facilities within a region that provide intravenous (and intra-arterial) tissue plasminogen activator and/or endovascular therapy.
B. Number of professionals within each organization/region trained and able to provide acute thrombolysis
Total number of ischemic stroke cases admitted to the ED or hospital (depending on local practices).
Total number of ischemic stroke cases admitted to the ED or hospital (depending on local practices).
Total number of ischemic stroke cases admitted to the ED or hospital (depending on local practices).
Number of health service facilities in the region (predefined).
Number of eligible healthcare professionals within each organization/ region
Data collected In development Data not collected Data not available
Data collected In development Data not collected Data not available
Data collected In development Data not collected Data not available
Data collected In development Data not collected Data not available
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The Roadmap to implementation of the WSO Global Stroke Guidelines and Action Plan includes
several modules that together address the full continuum of stroke care. The following modules are
available for you to use as part of stroke service planning, self-assessment and implementation. Each
Roadmap module includes the relevant service and resource checklist, applicable stroke best practice
recommendations and important key quality indicators. Some modules in the Roadmap include
additional elements and expanded information to those in the published WSO Global Stroke Care
Guidelines and Action Plan to be of further practical use for all sites.
Users of these tools are encouraged to review all modules of the Roadmap.
the following modules are available as part of the wSo Roadmap for Quality Stroke Care:
Introduction and Overview
1. Stroke System Development
2. Prehospital and Emergency Care
3. Acute Inpatient Stroke Care
4. Secondary Stroke Prevention
5. Stroke Rehabilitation
6. Community Reintegration and Long Term Recovery
world Stroke organization - Clinical Practice guideline http://www.world-stroke.org
Clinical Practice Guideline Guidelines recommended by the WSO Guidelines and Quality subcommittee.
WSO International Stroke Guildelines 2012; American Academy of Neurology guideline publication. Evidence-based Guideline: Prevention of stroke in nonvalvular atrial fibrillation. Summary of Evidence-based Guideline for CLINICIANS. Summary of Evidence-based Guideline for PATIENTS and their FAMILIES More information: https://www.aan.com/Guidelines/Home/ByTopic?topicId=20 Heart and Stroke Foundation resource for healthcare providers. Taking Action for Optimal Community and Long-Term Stroke Care (TACLS). French version: Agir en vue de soins optimaux communautaires et de longue durée de l’AVC.
© 2016, World Stroke Organization
Maria Grupper Executive Officer World Stroke Organization 7, rue Francois Versonnex PO Box 6053 CH 1211 Geneva 6, Switzerland Email: mgrupper@kenes.com
www.world-stroke.org
About the world Stroke organization
ouR viSion: A LIFE FREE OF STROKE.
OuR MISSION: The World Stroke Organization’s mission is to reduce the global impact of stroke through
prevention, treatment and long-term care. We work to reduce the impact of stroke on individuals,