Loading...

Messages

Proposals

Stuck in your homework and missing deadline? Get urgent help in $10/Page with 24 hours deadline

Get Urgent Writing Help In Your Essays, Assignments, Homeworks, Dissertation, Thesis Or Coursework & Achieve A+ Grades.

Privacy Guaranteed - 100% Plagiarism Free Writing - Free Turnitin Report - Professional And Experienced Writers - 24/7 Online Support

Week 1 respondo

03/09/2020 Client: carolinb Deadline: 24 Hours

 Response 1


Fluoroquinolones:


As a widely prescribed antibiotic, fluoroquinolones are used for the purpose of treating pneumonias, UTI’s, bronchitis, and sinusitis issues (Golomb, Koslik, & Redd, 2015). The pharmacokinetic property of fluoroquinolones is that they distributed throughout the body through the extracellular and intracellular fluids and concentrate in the lungs, prostate and bile (Werth, 2018). The Pharmacodynamic aspect of fluoroquinolones is that they work by targeting bacterial enzymes called DNA gyrase and topoisomerase IV. This action makes it hard for bacteria to multiply within the body, enhancing the effectiveness of this drug (Robinson & Woo, 2015).


Antilipidemics

The pharmacokinetic aspect of antilipidemic drugs, or statins, is that they are absorbed in the body through the liver, therefore increasing the livers ability to remove the bad cholesterol in the body.

The pharmacodynamic aspect of statins are that they inhibit the enzyme HMG-CoA reductase and therefore controls the rate of cholesterol production in the body (Robinson & Woo, 2015). When a patient is taking a statin, the effects are often shown to decrease the intracellular production of cholesterol. This was shown in a study of patients who were infected with HIV, and wanted to understand statin effects and protein regulation (Filippi et al., 2020).




Response 2


 


The Factors that Influence the Pharmacokinetics and Pharmacodynamics — Selective Serotonin Inhibitors and ACE Inhibitors


            Selective Serotonin and ACE Inhibitors are some of the popular groups of drugs. In this case, selective Serotonin Inhibitors such as citalopram, fluvoxamine, and escitalopram are administered in treating depression. They limit the blood from absorbing serotonin from the brain. The increase in this neurochemical in the brain relieves the level of depression (Woo, & Robinson, 2020). The pharmacokinetics of Angiotensin-converting enzyme inhibitors (ACEI) entails relaxing the blood vessels, resulting in low blood pressure. The ACEI prevents body enzymes from secreting angiotensin II, which is often responsible for vasoconstrictions of blood vessels associated with elevated blood pressure. Pharmacokinetics and pharmacodynamics of both drugs are subject to various factors, including genetics and patient demographics.


            For instance, the effectiveness of Selective Serotonin Inhibitors (SSIs) can be influenced by psychological factors like trait and state of anxiety and genetic factors. For instance, Tracy et al. (2016) explain that the metabolism of SSRIs is initiated by P450 (CYP) enzymes of the liver, which vary genetically to the extent that they affect the rate at which the drug is cleared. Indeed, the study by Maggo et al. (2019) revealed significant differences in correspondence between CYP2D6, CYP2C19, and CYP2C9 phenotypes of participants and history of tolerability of the antidepressant.


 Genetics also plays a crucial role in the pharmacokinetics and pharmacodynamics of ACE inhibitors. As documented by Flaten and Monte (2017), the ACE gene comes in variants associated with deletion, insertion of repetitions of Alu typical to intron 16. These variations have been linked to myocardial infarctions. A study on Malayan patients revealed that ACE can be effective for D/D genotype patients, as it is characterized by elevated ACE serum levels and activity that supports the inhibition process. The effectiveness is also subject to patient demographics such as gender. For instance, the rate of Angioedema, a common side effect, is common among women than men. This difference is attributable to the role of the C2399A variant among women. Moreover, ACE gene variants such as rs4267385 and rs4459610 are a protective factor against side effects such as coughs (Flaten and Monte, 2017). Therefore, physicians need to consider these factors when administering these drugs.


 


Your responses should be in a well-developed paragraph (300-350 words) to each peer. Integrating an evidence-based resource that is different than the one you used for the initial post.


Your responses to each peer’s chosen drug categories should include one evidence-based article that connects culture, genomics, pharmacogenomics, or a particular age group (infant or pregnancy, for example.)

Homework is Completed By:

Writer Writer Name Amount Client Comments & Rating
Instant Homework Helper

ONLINE

Instant Homework Helper

$36

She helped me in last minute in a very reasonable price. She is a lifesaver, I got A+ grade in my homework, I will surely hire her again for my next assignments, Thumbs Up!

Order & Get This Solution Within 3 Hours in $25/Page

Custom Original Solution And Get A+ Grades

  • 100% Plagiarism Free
  • Proper APA/MLA/Harvard Referencing
  • Delivery in 3 Hours After Placing Order
  • Free Turnitin Report
  • Unlimited Revisions
  • Privacy Guaranteed

Order & Get This Solution Within 6 Hours in $20/Page

Custom Original Solution And Get A+ Grades

  • 100% Plagiarism Free
  • Proper APA/MLA/Harvard Referencing
  • Delivery in 6 Hours After Placing Order
  • Free Turnitin Report
  • Unlimited Revisions
  • Privacy Guaranteed

Order & Get This Solution Within 12 Hours in $15/Page

Custom Original Solution And Get A+ Grades

  • 100% Plagiarism Free
  • Proper APA/MLA/Harvard Referencing
  • Delivery in 12 Hours After Placing Order
  • Free Turnitin Report
  • Unlimited Revisions
  • Privacy Guaranteed

6 writers have sent their proposals to do this homework:

Top Academic Guru
Buy Coursework Help
Smart Homework Helper
Writing Factory
Academic Master
Writer Writer Name Offer Chat
Top Academic Guru

ONLINE

Top Academic Guru

This project is my strength and I can fulfill your requirements properly within your given deadline. I always give plagiarism-free work to my clients at very competitive prices.

$35 Chat With Writer
Buy Coursework Help

ONLINE

Buy Coursework Help

I can help you with your project. I will make sure to provide you exceptional quality work within the required timeframe. Please message me so we can discuss the further details over chat.

$35 Chat With Writer
Smart Homework Helper

ONLINE

Smart Homework Helper

Greetings! I am the professional electrical, telecom engineer, rich experience in QPSK, OFDM, FFT, such signal processing concetps with matlab, I can satisfy you definitely. more in chat.thanks.

$55 Chat With Writer
Writing Factory

ONLINE

Writing Factory

I can help you with creating a presentation of one slide for The Word of William Hunter. I will be happy to offer you 100% original work with high-quality standard, professional research and writing services of various complexities.

$25 Chat With Writer
Academic Master

ONLINE

Academic Master

I have super grip on essays, case studies, reports and discussion posts. I am working on this forum from last 6 years with full amount of satisfaction of my clients.

$40 Chat With Writer

Let our expert academic writers to help you in achieving a+ grades in your homework, assignment, quiz or exam.

Similar Homework Questions

Why our campuses are safer without concealed handguns - River riding math worksheet answer - The black and decker corporation case study - Life ming yuan pore strips directions - Examination day by henry slesar analysis - 6 indicators of chemical change - A gift of fire sara baase 4th edition pdf free - Manzana insurance process flow diagram - Reporting descriptive statistics apa - I need help with managerial Finance assignment. - Revise - IW2D1 - Exp 105 week 3 chapter quiz - Koppersmith v state case brief - Poweredge vrtx technical guide - Iolp level 3 example - True or false a convex shape curves outwards - Atavist business model - In the context of dollar-value lifo, what is a lifo layer? - Which of the following statements is true about naturalistic observation - International seminary plymouth florida - 8.1 describing chemical reactions - Number of orders per year formula - 2 D.B and 1 Assignment - Eaton easy 821 dc tc manual - The crucible essay conclusion - The jilting of granny weatherall worksheet answers - Chess holding statement commsec - Case study - Evan company reports net income of - Romeo and juliet 2014 - Fox body stand alone engine management - Mcgraw hill connect economics homework answers - Economic Principles – Microeconomics - Louis vuitton case study solution - Essay - Australian national bulldog club - Data visualization makes complex data more _______________ - Engagement survey and action work plan - English - List the factors of 29 - At penn foster expanded academic asap is - Mr smith keeps track of his students homework completion - Building intelligence center hvac - Clear post study career plan - Best definition of accounting - Inverted u theory graph - Glb ethics and law - Module c craft of writing prescribed texts - The oceanaire seafood room menu - Sostac model case study - How to calculate sxy - Does stiles have adhd - Hp bl460c gen8 quickspecs - Is 522 exercising continuity plans for pandemics answers - Week 1 Discussion - Student exploration calorimetry lab answers activity b - How to prepare oxygen in a laboratory - 17 assignment leadership - 3.11 defying archetypes - Shammi prasad brother's names - Capability maturity model integration cmmi - Compensating subjects of a research study is ethical blank - 4 types of innovation invention extension duplication synthesis - No gumption by russell baker questions and answers - Romeo and juliet short answer questions - Whole foods case study - In adjourning, conflicts are resolved, close relationships develop, and unity and harmony emerge. - Bangladesh high commission canberra - Write and read - You ll never walk alone karaoke female version - Present perfect subjunctive sentences - Molarity of solutions worksheet answers - Outliers in data set independent practice worksheet answers - Sylvia mathews burwell net worth - Criminal Justice/discussion - Algebra 2 final exam - MKTG201 Week 4 Midterm Exam - Thomas berry the great work pdf - Air enters an evaporative cooler at atm - Cold joint termite protection - The inspiration of mr budd sparknotes - Landmark house hammersmith bridge road - My body politic - First pass effect drug examples - WEEK VIII PT 2A - Hr - The invalid's story critical thinking answers - The primary aim of social marketing is: - Arbonne lemon protein balls - 17th edition amendments free download - MBA 6601 POWER POINT UNIT II - Please check the doc and respond-24 hours to comp the work - M4a1 - Social welfare case studies - Ideal gas law experiments high school - Forces in 1 dimension - Nrl number plates nsw - Meaning of case study - Donabedian theory of quality health care