he goal of this assignment is to show that you understand the importance of the liver, pancreas, and kidneys in the proper functioning of the human body.
a 63-year-old female with a past medical history significant for diabetes mellitus, cirrhosis, gout, and a 30-pack a year smoking history, presents to the emergency room
with chest pain revealing pericarditis in the echocardiogram, secondary to recently diagnosed end-stage renal disease. Physical examination reveals yellowish discoloration to the skin and sclera, multiple bruises, and 2+ bilateral edema. Sarah reports weakness lasting more than three weeks. Her medications include Glisten, a new drug for diabetes that causes ATP sensitive potassium channels to close, thereby releasing insulin.
Her recent laboratory results are as follows:
CBC
Sodium
126 mEq/L
Glucose
220 mmol/L
Calcium
7.1 mg/dl
Red blood cell count
3.9 cells / ul
Vitals
Blood pressure
92/64 mmHg
Blood Gases
pH
7.28
CO2
30 mmHg
HCO3
12 mmol/L
Hormone Panel
Renin
Low
ADH
Elevated
Aldosterone
Low
Vitamins
Vit D
low
Vit K
low
Vit E
low
Vit A
low
Urine and Stool Sample
Stool color
Gray
Stool content
Increased fat content
Urine color
White
Attached please find the case study questions
Address each of the following regarding Sarah’s case:
Explain the cause for her low calcium and sodium levels.
Explain the cause of her anemia. What laboratory test should indicate she is suffering from anemia?
Explain the cause of her hypotension. How will her body attempt to establish homeostasis?
What type of acid-base disorder has she developed, and how will her body compensate?
Explain the cause of her elevated ADH and glucose levels.
What is the correlation between her illnesses and the low vitamins (D, K, E, and A), renin, and aldosterone levels?
Which hormone would the body elevate in response to her low calcium levels? Why?
Explain the physiological reason behind her physical findings (yellowish hint of the skin, sclera, multiple bruises, weakness, and edema).
Explain the cause of her abnormal stool and urine sample.
What cell does Glisten work on? Explain how this medication is able to stimulate insulin secretion.
Specifics
Support your opinions with evidence from your readings and research.
You must reference a minimum of three (3) scholarly sources in your paper, which includes one non-Internet source.
Use current APA format to style your paper and to cite your sources.
Your paper/total responses must be 3–4 pages in length not including the title page, abstract, and reference pages.
For your signature assignment, compose a 3- to 4-page case analysis (in addition to a title, abstract, and a reference page) written in APA format with at least 3 references, with one non-Internet reference.
The following should be covered in the paper:
• Title page: Case title, full name, section, date, instructor, and campus
• Abstract: Summarize the case.
• Introduction: Explain the physiological importance of the liver, pancreas, and kidneys for the proper functioning of the human body.
• Body: Respond to the prompts. Organize your analysis with headings that thoroughly answer the prompts (e.g., “Calcium and Sodium Imbalance” should be the heading for question 1).
• Conclusion: Summarize the paper in a paragraph. By submitting this paper, you agree to the following:
End-Stage Kidney Disease Sarah, a 63-year-old female with a past medical history significant for diabetes mellitus, cirrhosis, gout, and a 30-pack a year smoking history presents to the emergency room with chest pain revealing pericarditis in the echocardiogram, secondary to recently diagnosed end-stage renal disease. Physical examination reveals yellowish discoloration to the skin and sclera, multiple bruises, 2+ bilateral edema, and weakness lasting more than three weeks. Her medications include Glisten, a new drug for diabetes that causes ATP sensitive potassium channels to close, thereby releasing insulin. Her recent laboratory results are as follows:
CBC Sodium 126 mEq/L
Glucose 220 mmol/L
Calcium 7.1 mg/dl
Red blood cell count 3.9 cells/ul
Vitals Blood Pressure 92/64 mmHg
Blood Gases pH 7.28 CO2 30 mmHg
HCO3 12 mmol/L Hormone Panel Renin Low ADH Elevated Aldosterone Low Vitamins Vit D Low Vit K Low Vit E Low Vit A Low Urine and Stool Sample Stool color Gray Stool content Increased Fat Content Urine color White Rev 12-17-17 Please address each of the following regarding Sarah’s case:
1. Explain the cause for her low calcium and sodium levels.
2. Explain the cause of her anemia. What laboratory test should indicate she is suffering from anemia?
3. Explain the cause of her hypotension. How will her body attempt to establish homeostasis?
4. What type of acid-base disorder has she developed, and how will her body compensate?
5. Explain the cause of her elevated ADH and glucose levels.
6. What is the correlation between her illnesses and the low vitamins (D, K, E, and A), renin, and aldosterone levels?
7. Which hormone would the body elevate in response to her low calcium levels? Why? 8. Explain the physiological reason behind her physical findings (yellowish hint of the skin, sclera, multiple bruises, weakness, and edema). 9. Explain the cause of her abnormal stool and urine sample. 10. What cell does Glisten work on? Explain how this medication is able to stimulate insulin secretion.