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1) Compare and contrast SN1, SN2, E1, and E2 reactions! (similarities abd differences. Requirements for each to work.)
2) Why is SN2 is in direct competition with E2 while SN1 is direct competition with E1 reaction.
3) Rate expression of each
4) which reactions are concerted? Which are atep wise?
5) which are sterospecific and what stereospecificity of each are?
6) how do the variables below (A-D) influence reaction pathway?
Compare and contrast SNI, SN2, El and E2 reactions. What are some obvious similarities and differences between each reaction
Compare and contrast SNI, SN2, El and E2 reactions. What are some obvious similarities and differences between each reaction pathway? What are the requirements for each reaction to work? Discuss why SN2 is in direct competition with E2 while SNL is in direct competition with the El reaction pathway. What is the rate expression for each? Which reactions are concerted? Which reactions are step-wise? Which reactions are stereospecific and what is the stereospecificity of each that are? How do the variables below help influence which reaction pathway will lead to the major product formed? a. Substrate (substitution pattern and leaving group ability) b. Nucleophile/base strength (weak or strong and size (unhindered or hindered) c. Solvent (polar-aprotic or polar-protic) d. Temperature (low/ambient temps vs. higher temps)
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